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Showing Category: Knowledge Base PS7

Can I create a duplicate/copy of an entity?

Yes, you can clone an entity in a pathway.  To perform this, first the entity must have multiple relations.  Entity cloning makes a visual copy of...

11/25/2008 Category: Working with Pathways

Can I display the trend of my intensity data for individual probes on the graphical view?

Yes, you can display your intensity data in a diagram view when you have imported intensity or log-intensity data into Pathway Studio.

Diagrams show the...

07/14/2009 Category: Experimental Data Analysis

Can I edit the relationship type or direction?

Figure 3.

This is done by double-clicking on the relationship in the graph view to open the Relation view.

 

Go to the “Linked Entities” tab (Figure 2) to see the...

08/05/2008 Category: Working with Pathways

Can I export references from Pathway Studio and import into EndNote?

1. Open pathway of interest.2. In the Pathway view select Tools > Pathway Reference Summary.      3. Click "Save EndNode..." button...

12/05/2008 Category: Working with Pathways

Can I filter a pathway based on confidence?

It is possible to sort the relationships based on the number of references that support that relationship found in the database.  Relationships with a...

08/12/2008 Category: Working with Pathways

Can I install Pathway Studio on a Mac desktop or laptop?

Pathway Studio is not designed for operation on a Macintosh with MacOS and Ariadne does not plan to add the support of this operating system in the...

03/30/2009 Category: Installation and Maintenance

Can I optimize the extraction of information from PubMed with MedScan using the Plant Cartridge?

As the proportion of abstracts related to Plant in PubMed is low, it is worthwhile to use the advanced search options available in PubMed to enrich for plant...

05/21/2009 Category: MedScan Text Mining Tools

Can I put a group in a pathway?

In Pathway Studio 6 you cannot put a group in a pathway.  The individual members of a group can be put into the pathway as individual entities.

08/05/2008 Category: Working with Pathways

Can I select all the relationships for one specific entity in a complex pathway graph?

You can easily select all the relationships for one entity by performing the following steps:

1.  In the pathway view select the entity of...

12/11/2008 Category: Working with Pathways

Can I view two pathways at the same time?

Yes, you can view two (or more) pathways at the same time.  Simply select: Cascade Document Windows or Tile Document Windows from the Windows menu above...

11/25/2008 Category: Working with Pathways

Do relations to a functional class in a pathway include known relations to the proteins contained in the functional class?

Functional classes are a recognized type of entity within Pathway Studio.  Relations to the functional class are specifically for the functional class...

01/21/2009 Category: Working with Pathways

Does Pathway Studio support import for Affymetrix GeneChip HG_U95Av1 and MU_72v1?

Yes.  Pathway Studio does support import for these withdrawn chips, however Ariadne does not have access to the .CDF files, required to analyze these...

08/18/2008 Category: Working with Pathways, Experimental Data Analysis

How are contradictory relation findings resolved in Pathway Studio?

Relations are supported by facts extracted from the literature using MedScan, a Natural Language Processing (NLP) tool developed by Ariadne....

07/31/2009 Category: Working with Pathways, ResNet Databases and Ontologies

How are Gene Set Enrichement Analysis and Sub-Network Enrichement Analysis calculated?

Sub-Network Enrichment Analysis (SNEA)

The following steps describe the computational steps performed in SNEA.

1.)  Preparation of Sub-NetworksSNEA...

11/25/2008 Category: Experimental Data Analysis

How are the different pathway layout options calculated and what do they represent?

Figure 1.

Pathway Studio comes equipped with multiple layout options: (Cellular) Localization, DirectForce, Hierarchical and Symmetrical. Select Layout on the pathway...

08/05/2008 Category: Working with Pathways

How are the Functional Classes colorized with experimental data when they contain more than one measured gene/protein?

A Functional Class can contain multiple proteins. By default, the color of this entity will be the color of the gene/protein that has the lowest p-value, if...

02/20/2009 Category: Experimental Data Analysis

How can I access the literature and the number of references supporting a relation in Pathway Studio

There are different options to access the literature and the number of references supporting a relation in Pathway Studio:1. From the Graphical View, put your...

08/26/2009 Category: Working with Pathways, Experimental Data Analysis

How can I add proteins to a functional class located in the public space of a remote ResNet database in Pathway Studio Enterprise?

You can add a protein to a functional class directly in the public space using an account with ‘Editor’ role and via the webclient (This functionality is...

01/18/2010 Category: Working with Pathways, ResNet Databases and Ontologies

How can I add proteins to a functional class?

You can add proteins to an existing functional class or a newly created functional class by doing the following:

1. Open a new pathway and add to the...

11/24/2008 Category: Working with Pathways, ResNet Databases and Ontologies

How can I attribute a specific shape to all miRNA in the ResNet database?

In ResNet 7 database, miRNA belongs to the protein entity category. By default, the miRNA shape is an ellipse, the generic protein shape in ResNet. To...

10/21/2009 Category: Working with Pathways, ResNet Databases and Ontologies

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