Toll-like receptor -> NF-kB signaling pathway

Toll-like receptor -> NF-kB signaling pathway has been created using Ariadne's Pathway Studio and ResNet Database of over 1.5 Million molecular interactions and functional relationships. The pathway diagram is interactive: click on entities and relations to retrieve additional information and literature references. You can check the meaning of different shapes and colors using the Legend.

ariadne genomics inc. flagellins nfkbia ---| nf-kb irak1 irak4 map3k7 tlr9 ly96 ---- tlr4 lps myd88 ---- tlr4 flagellins ---- tlr5 ikbk myd88 ---- tlr7 irak1 --+> traf6 irak4 --+> irak1 cd14 cd14 ---- tlr4 nf-kb myd88 cpg dna ---- tlr9 traf6 --+> map3k7 ikbk ---| nfkbia map3k7 --+> ikbk tirap myd88 --+> irak4 cpg dna myd88 ---- tlr9 tirap --+> irak1 tlr4 tlr4 --+> tirap tlr7 tlr5 myd88 ---- tlr5 traf6 imidazoquinoline ---- tlr7 nfkbia ly96 lps ---- tlr4 imidazoquinoline Toll-like receptor -_ NF-kB signaling pathway