Protein tyrosine phosphatase receptor signaling pathway

Protein tyrosine phosphatase receptor signaling pathway has been created using Ariadne's Pathway Studio and ResNet Database of over 1.5 Million molecular interactions and functional relationships. The pathway diagram is interactive: click on entities and relations to retrieve additional information and literature references. You can check the meaning of different shapes and colors using the Legend.

ariadne genomics inc. dag --+> rasgrp1 ip3 --+> itpr1 itpr1 sos1 --+> ras ca2+ --+> rasgrf1 ca2+ --+> rasgrp1 dag --+> rasgrf1 ras --+> raf1 vav1 --+> itk sos1 map2k1 --+> mapk3 bcl6 lck --+> plcg1 plcg1 itpr1 --+> ca2+ map2k2 --+> mapk1 raf1 --+> map2k1 itk --+> plcg1 ptprc dag grb2 rasgrf1 --+> ras fyn fyn --+> plcg1 lck rasgrf1 map2k1 ras vav1 itk map2k2 rasgrp1 --+> ras map2k2 --+> mapk3 raf1 --+> map2k2 ptprc --+> fyn map2k1 --+> mapk1 grb2 --+> sos1 ip3 fyn --+> vav1 grb2 ---- ptprc dag; plcg1; ip3 mapk1 ca2+ mapk3 mapk3 ---| bcl6 ptprc --+> lck mapk1 ---| bcl6 rasgrp1 raf1 Protein tyrosine phosphatase receptor signaling pathway