Notch -> HES/HEY signaling pathway

Notch -> HES/HEY signaling pathway has been created using Ariadne's Pathway Studio and ResNet Database of over 1.5 Million molecular interactions and functional relationships. The pathway diagram is interactive: click on entities and relations to retrieve additional information and literature references. You can check the meaning of different shapes and colors using the Legend.

ariadne genomics inc. ncor2 ---- rbpj rfng ---> notch mfng ---> notch gamma-secretase ctbp1 ---- hdac1 lfng ---> notch jag1 ctbp1 rfng rbpj --+> hey1 notch --+> rbpj adam17 dll1 --+> notch lfng notch dvl1 ---| notch jag1 --+> notch dvl1 rbpj cir ---- rbpj hes1 hey1 hdac1 ---- ncor2 adam17 --+> notch cir numb maml1 gamma-secretase --+> notch dll1 hdac1 ---- rbpj cir ---- ncor2 hdac1 mfng numb ---| notch rbpj --+> hes1 notch ---| dll1 ncor2 maml1 --+> rbpj Notch -_ HES_HEY signaling pathway