IL-6 -> STAT signaling

IL-6 -> STAT signaling pathway has been created using Ariadne's Pathway Studio and ResNet Database of over 1.5 Million molecular interactions and functional relationships. The pathway diagram is interactive: click on entities and relations to retrieve additional information and literature references. You can check the meaning of different shapes and colors using the Legend.

ariadne genomics inc. jak1 --+> stat3 tyk2 --+> stat3 il6 --+> il6r il6 il6st --+> tyk2 il6r ---- jak2 jak1 --+> stat1 jak1 --+> jak2 il6st --+> jak2 jak2 --+> jak1 il6st --+> jak1 il6r ---- tyk2 jak2 --+> stat3 il6r ---- il6st jak2 --+> stat1 jak1 jak2 tyk2 il6r il6r ---- jak1 tyk2 --+> stat1 stat1 il6st stat3 IL-6 -_ STAT signaling pathway