B-cell receptor -> NF-kB signaling

B-cell receptor -> NF-kB signaling pathway has been created using Ariadne's Pathway Studio and ResNet Database of over 1.5 Million molecular interactions and functional relationships. The pathway diagram is interactive: click on entities and relations to retrieve additional information and literature references. You can check the meaning of different shapes and colors using the Legend.

ariadne genomics inc. immunoglobulin pip3 pip3 --+> btk lyn --+> syk nfkbia ---| nf-kb syk lyn plcg2 --+> dag dag --+> pkc nfkbia cd79a ---- lyn cd79b traf6 cd79a malt1 bcl10 ---- malt1 pi3k syk --+> plcg2 card11 ---- malt1 antigen ---- immunoglobulin lyn --+> pi3k btk cd79a ---- immunoglobulin map3k7 --+> ikbk ikbk ---| nfkbia cd79b ---- immunoglobulin traf6 --+> map3k7 nf-kb cd79a ---- cd79b malt1 ---- traf6 bcl10 ---- card11 pkc --+> bcl10 pkc pi3k --+> pip3 dag bcl10 ---- traf6 plcg2 card11 btk --+> plcg2 cd79b ---- lyn map3k7 antigen bcl10 ikbk B-cell receptor -_ NF-kB signaling pathway