B-cell receptor -> NFATC signaling

B-cell receptor -> NFATC signaling pathway has been created using Ariadne's Pathway Studio and ResNet Database of over 1.5 Million molecular interactions and functional relationships. The pathway diagram is interactive: click on entities and relations to retrieve additional information and literature references. You can check the meaning of different shapes and colors using the Legend.

ariadne genomics inc. immunoglobulin pip3 --+> btk lyn --+> syk calcineurin --+> nfatc3 nfatc1 pip3 syk lyn calcineurin --+> nfatc2 cd79a ---- lyn cd79b plcg2 --+> ip3 itpr1 ca2+ cd79a pi3k syk --+> plcg2 ip3 antigen ---- immunoglobulin lyn --+> pi3k btk cd79a ---- immunoglobulin ip3 --+> itpr1 calcineurin --+> nfatc4 cd79b ---- immunoglobulin calcineurin --+> nfatc1 cd79a ---- cd79b nfat5 pi3k --+> pip3 nfatc4 plcg2 nfatc3 itpr1 --+> ca2+ calcineurin btk --+> plcg2 cd79b ---- lyn nfatc2 calcineurin --+> nfat5 ca2+ --+> calcineurin antigen B-cell receptor -_ NFATC signaling pathway