MAPK-ERK in Growth and Differentiation Pathway

Ariadne includes the MAPK-ERK in Growth and Differentiation Pathway in ResNet as part of the canonical pathway collection. The pathway diagram is interactive: click on entities and relations to retrieve additional information and literature references.

In Pathway Studio, you can edit the MAPK-ERK in Growth and Differentiation Pathway.  You can add new entities and relations manually or expand it using the ResNet database of functional relationships extracted from literature.  You can also use the pathway for analysis of  your gene expression data.

ariadne genomics inc. shc1 growth factors growth factor receptor plcg2 fyn grb2 rac gtpase pak3 raf1 braf ptk2b src ptk2 pxn u0126 pd98059 rps6k srf histone mknk1 translation mknk2 dusp1 integrin tln1 pparg gpcr estrogen receptor protein phosphatase pkc epac atf4 pla2g1b fos myc elk1 ion channel mapk3 mapk1 mapkapk2 arc dusp6 sos1 ras small monomeric gtpase ksr crk grf2 rap1a map2k2 map2k1 ca2+ camp rho small monomeric gtpase phosphatidylinositol 3-kinase pak2 pak1 pka stat3 stat1 MAPK-ERK in Growth and Differentiation pathway