EGF Signaling Pathway

Ariadne includes the EGF Signaling Pathway in ResNet as part of the canonical pathway collection. The pathway diagram is interactive: click on entities and relations to retrieve additional information and literature references.

In Pathway Studio, you can edit the EGF Signaling Pathway.  You can add new entities and relations manually or expand it using the ResNet database of functional relationships extracted from literature.  You can also use the pathway for analysis of  your gene expression data.

ariadne genomics inc. erk activator kinase diacylglycerol pip2 egfr egf srf jun mapk8 mapk1 sos2 ras small monomeric gtpase rasa1 shc1 plcg2 raf1 map3k1 map2k4 jak1 grb2 ca2+ stat3 stat1 pkc inositol 1,4,5-trisphosphate fos transcription elk1 protein kinase ck2 protein phosphatase EGF signaling pathway