Death Receptor Signaling Pathway

Ariadne includes the Death Receptor Signaling Pathway in ResNet as part of the canonical pathway collection. The pathway diagram is interactive: click on entities and relations to retrieve additional information and literature references.

In Pathway Studio, you can edit the  Death Receptor Signaling Pathway.  You can add new entities and relations manually or expand it using the ResNet database of functional relationships extracted from literature.  You can also use the pathway for analysis of  your gene expression data.

ariadne genomics inc. tnfrsf1a tnf smac apaf1 cyc1 bid dna fragmentation dna repair necrosis casp2 nuclear factor nf kappa b ikappab ikappab kinase nf-kappab-inducing kinase casp9 casp8 casp3 map3k5 mapk8 rock1 fadd cradd ripk1 tradd dr3 tnfsf12 tnfrsf6 tnfsf6 cflar tnfrsf10b casp10 tnfrsf10a tnfsf10 membrane blebbing gas2 traf2 sptan1 dffb dffa casp6 map2k7 apoptosis inhibitor casp7 bcl2 chromatin condensation acinus parp1 daxx actin lmna Death receptor signaling pathway