Apoptosis Pathway

Ariadne includes the apoptosis pathway in the ResNet database as part of the canonical pathway collection. The pathway diagram is interactive: click on entities and relations to retrieve additional information and literature references.

In Pathway Studio, you can edit the apoptosis pathway.  You can add new entities and relations manually or expand it using the ResNet database of functional relationships extracted from literature.  You can also use the pathway for analysis of  your gene expression data.

 

ariadne genomics inc. gsk-3 fileadmin/pathways/collections/apoptosis app casp6 cyc1 apaf1 casp8 akt1 casp10 bad rps6k erk activator kinase raf1 ras small monomeric gtpase growth factor receptor cytokine nuclear factor nf kappa b casp12 tnfrsf1a tnf endoplasmic reticulum tnfrsf6 tnfsf6 smac bcl2 bcl2l1 mapk8 bax tp53 fileadmin/pathways/collections/apoptosis inhibitor membrane blebbing dna repair casp3 map3k5 ca2+ calpain nf-kappab-inducing kinase casp9 mapk3 mapk1 pkc growth factors cytokine_receptor phosphatidylinositol 3-kinase pdpk1 casp7 foxo1a dna fragmentation inositol 1,4,5-trisphosphate Apoptosis pathway