ResNet Mammalian Database
ResNet Mammalian includes curated signaling and cellular process regulation pathways, as well as ontologies and annotations, and a database of molecular interactions extracted from the entire PubMed (17,000,000 abstracts) and 61 full text journals that can be used for data mining and pathway building. It contains information on over 1.5 million functional relationships for human, rat, and mouse, linked to all of their original literature sources.
The database is located at the user’s computer or server and can be modified and curated. You can use MedScan to process publications or internal text sources and extract information to add to the ResNet database.
STATISTICS FOR RESNET MAMMALIAN
- Over 1.5 million relations for:
- 110,435 proteins
- 13,533 small molecules
- 2814 cellular processes
- 2,410 diseases
- Pathways:
- 227 Receptor signaling pathways
- 21 new cellular process regulation pathways
- Atlas of Signaling - all cellular signaling on one map
- Ontologies:
- Gene Ontology
- Ariadne protein ontology
- Annotations:
- Entrez Gene protein annotations
- Protein annotations (aliases, GO annotation, protein cell localization, and database references) from Dana-Farber Cancer Institute and Harvard School of Public Health
- Small Molecule attributes (aliases, PubChem Identifiers, and CAS registry numbers)
- MedScan dictionary annotations for cell processes and diseases
ARIADNE ONTOLOGY AND PATHWAY COLLECTION
ResNet Mammalian database includes Ariadne’s proprietary protein ontology where 8,666 genes are organized in 504 groups, and 249 signaling and cellular process pathways organized in folders. It also includes an “Atlas of Signaling” pathway which represents a global overview of cell signaling on a single pathway diagram.
You can modify and expand Ariadne’s pathways using Pathway Studio tools and data from ResNet database, or by adding information from recently published or internal texts using MedScan tool.
