ResNet Mammalian Database
ResNet Mammalian includes curated signaling, cellular process and metabolic pathways, ontologies and annotations, as well as molecular interactions and functional relationships extracted from the entire PubMed (19,000,000 abstracts) and 61 full text journals.
The database can be used for data mining and pathway building. It contains information on over 715,000 functional relationships for human, rat, and mouse, linked to all of their original literature sources.
ResNet is located at your own computer or server and can be modified and curated. You can use MedScan tool in Pathway Studio to process publications or internal text sources and extract information to add to the database.
STATISTICS FOR RESNET MAMMALIAN
- Over 715,000 relations for:
- 106,139 proteins
- 1220 small molecules
- 2175 cellular processes
- 3930 diseases
- Pathways:
- 227 Receptor signaling pathways
- 21 new cellular process regulation pathways
- 39 metabolic pathways
- Atlas of Signaling - all cellular signaling on one map
- Ontologies:
- Gene Ontology
- Ariadne protein ontology
- Annotations:
- Protein annotations: Entrez Gene ID, SwissProt ID, GeneBank ID, Homologene ID, MGI ID, RGD ID, Hugo ID, Unigene ID and also
- Aliases, protein cell localizations, and database references
- Small Molecule attributes: aliases, PubChem Identifiers, CAS registry numbers, and ChEBI ID
- MedScan dictionary annotations for cell processes and diseases
ARIADNE ONTOLOGY AND PATHWAY COLLECTION
ResNet Mammalian database includes Ariadne’s proprietary protein ontology: almost 9000 genes are organized in 506 groups, and 287 signaling, cellular process, and metabolic pathways are organized in folders. It also includes an “Atlas of Signaling” pathway which represents a global overview of cell signaling on a single pathway diagram.
You can modify and expand pathways using data from the ResNet database, or by adding information from recently published or internal texts using MedScan tool.
