Protein : APC


Owner	Public
URN	urn:agi-llid:324
Hugo ID	583
Connectivity	271
Name	APC
Description	adenomatosis polyposis coli
Notes	binds microtubules; may play a role in the regulation of cell polarity [RGD]


RGD ID	2123


MGI ID	88039


Cell Localization	Nucleus


Pathway	Wnt signaling


Group	cell adhesion
	signal transduction
	Wnt receptor signaling pathway
	cell cycle
	regulation of progression through cell cycle
	negative regulation of progression through cell cycle
	establishment and-or maintenance of cell polarity
	anterior-posterior pattern formation
	axis specification
	dorsal-ventral pattern formation
	protein complex assembly
	cytoplasm
	nucleus
	lateral plasma membrane
	binding
	peroxidase activity
	protein binding
	beta-catenin binding
	microtubule binding


GenBank ID	NC_000005
	NM_000038
	NP_000029
	NT_034772
	NW_922751
	AC_000048
	AC008575
	AC136500
	AF127506
	AAF34355
	AF297219
	AAG25599
	AY682982
	AAT81590
	AY900441
	AAW82777
	AY925197
	AAX07544
	S78214
	AAB21145
	AB210001
	BAE06083
	AI492038
	BC034955
	BC056268
	AAH56268
	BC111462
	AAI11463
	BC111591
	AAI11592
	BC111930
	AAI11931
	BE047584
	BF112110
	BG548363
	BM271918
	BM713901
	BM975470
	CA313732
	M73548
	AAA60353
	AAA60354
	M74088
	AAA03586
	S67787
	AAD13997
	S67788
	AAD13998
	P25054
	Q16097
	Q5EBR9
	Q5EEK4
	Q6B4H6
	Q7Z2Q8
	Q9HAW6
	Q9P119
	Q9UM98
	NC_000084
	NM_007462
	NP_031488
	NT_039674
	NT_039681
	XM_622559
	XP_622559
	NW_000134
	NW_001030631
	AC_000040
	AC090534
	AC091750
	AL591373
	U02937
	AAA03443
	AK037764
	AK039061
	AK039745
	AK042021
	BAC31134
	AK045053
	BAC32198
	AK046280
	AK048709
	AK054067
	AK080907
	BAC38073
	AK082724
	BAC38587
	AK137301
	AK142170
	BAE24957
	BB316435
	BG069851
	BG070122
	BG076990
	BM124893
	BM245154
	L19608
	AAN87116
	M88127
	AAB59632
	Q61315
	NC_005117
	NM_012499
	NP_036631
	NW_001084735
	NW_047510
	AC_000086
	D38629
	BAA07609
	P70478


Source	Curated


LocusLink ID	324
	11789
	24205


Organism	Homo sapiens
	Mus musculus
	Rattus norvegicus


OMIM ID	175100
	135290
	137215
	155255
	276300


Alias	GS
	DP2
	DP3
	FAP
	FPC
	DP2.5
	adenomatosis polyposis coli
	tumor suppressor
	adenomatous polyposisi coli
	adenomatous polyposis coli protein
	adenomatosis polyposis coli tumor suppressor
	Min
	AI047805
	AU020952
	AW124434
	multiple intestinal neoplasia
	RATAPC


GO ID	0008013
	0008017
	0016055
	0007155
	0007049
	0045786
	0006461
	0007165
	0016328
	0005634
	0005488
	0004601
	0005515
	0009952
	0009798
	0009953
	0000074
	0005737
	0007163


Swiss-Prot Accession	P25054
	Q16097
	Q5EBR9
	Q5EEK4
	Q6B4H6
	Q7Z2Q8
	Q9HAW6
	Q9P119
	Q9UM98
	Q61315
	P70478


Unigene ID	Hs.158932
	Mm.7883
	Mm.384171
	Rn.88057