Protein : IKBKB
Owner Public
URN urn:agi-llid:3551
Hugo ID 5960
Connectivity 867
Name IKBKB
Description inhibitor of kappaB kinase beta
Notes kinase that may be involved in megakaryocyte polyploidization [RGD]
RGD ID 621375
MGI ID 1338071
Pathway NF kappa B
TNFR2 signaling
Toll-Like Receptor pathway
Group Kinases
I-kappaB phosphorylation
protein amino acid phosphorylation
activation of NF-kappaB transcription factor
B cell homeostasis
cytoplasm
nucleotide binding
protein binding
ATP binding
transferase activity
kinase activity
protein kinase activity
protein serine-threonine kinase activity
protein-tyrosine kinase activity
receptor signaling protein serine-threonine kinase activity
transcriptional activator activity
GenBank ID NC_000008
NM_001556
NP_001547
NT_007995
NW_923907
AC_000051
AC083973
AY663108
AAT65965
AB209090
BAD92327
AF029684
AAC51860
AF031416
AAC64675
AF080158
AAD08997
AK023193
AK091297
AL708460
BC006231
AAH06231
BC090865
BC108694
AAI08695
BX648165
CR607076
O14920
Q59GL9
NC_000074
NM_010546
NP_034676
NT_039457
NW_000339
NW_001030892
AC_000030
AC121835
AF026524
AAC23557
AF088910
AAD52095
AI447910
AK003927
AK011359
BAE43224
AK051128
BAC34533
AK053346
AK086442
AK139972
BAE24202
AK144603
BAE25962
AK150884
BAE29931
AK151888
AK151955
BAE30827
AK153151
BAE31761
AK155587
AK156294
BAE33659
AK172275
BAE42920
AK177348
AK182153
AK186184
AK194273
AK201390
AK219506
BB525754
BC004772
BC019210
BC020334
BC037723
AAH37723
BG074590
BG087220
O88351
Q5D0E0
NC_005115
NM_053355
NP_445807
NW_001084719
NW_047475
AC_000084
AF115282
AAF21978
Q9QY78
Source Curated
LocusLink ID 3551
16150
84351
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 603258
Alias IKK2
IKKB
NFKBIKB
IKK-beta
MGC131801
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
nuclear factor NF-kappa-B inhibitor kinase beta
inhibitor of nuclear factor kappa B kinase beta subunit
IKK-2
IKK[b]
AI132552
inhibitor of kappaB kinase beta
AIM-1
inhibitor of kappa light polypeptide gene enhancer in B-cells kinase beta
GO ID 0005524
0000166
0005515
0004674
0004713
0016563
0016740
0051092
0006468
0005737
0016301
0004672
0004702
0001782
0007252
Swiss-Prot Accession O14920
Q59GL9
O88351
Q5D0E0
Q9QY78
Unigene ID Hs.413513
Mm.277886
Rn.19222