Protein : CD14
Owner Public
URN urn:agi-llid:929
Hugo ID 1628
Connectivity 668
Name CD14
Description CD14 antigen
Notes component of the lipopolysaccharide receptor complex; mediates LPS-induced neuroinflammation and inflammatory response [RGD]
RGD ID 620588
MGI ID 88318
Cell Localization Plasma membrane
Pathway Toll-Like Receptor pathway
TLR2/4/5/7/9 -> AP-1 signaling pathway
TLR4 -> IRF3/7 signaling pathway
TLR4/5/7/9 -> NF-kB signaling pathway
Group Receptors
cell surface receptor linked signal transduction
apoptosis
phagocytosis
inflammatory response
immune response
membrane
plasma membrane
extrinsic to membrane
lipopolysaccharide receptor complex
extracellular space
GPI anchor binding
peptidoglycan receptor activity
GenBank ID NC_000005
NM_000591
NP_000582
NT_029289
NW_922784
AC_000048
NM_001040021
NP_001035110
AC116353
X06882
CAA29999
AF097942
AAC83816
AY044269
AAL02401
BC010507
AAH10507
BT007331
AAP35995
CR590334
CR590355
CR590525
CR591451
CR594268
CR595571
CR598974
CR600557
CR600702
CR601474
CR602302
CR603424
CR605705
CR609600
CR610580
CR610684
CR612020
CR613552
CR614015
CR614726
CR616071
CR617446
CR620138
CR620234
CR620555
CR626311
DA681405
M86511
AAA51930
X13334
CAA31711
P08571
Q53XT5
NC_000084
NM_009841
NP_033971
NT_039674
NW_000134
NW_001030631
AC_000040
AB039054
BAB68578
AB039055
BAB68579
AB039056
BAB68580
AB039057
BAB68581
AB039058
BAB68582
AB039059
BAB68583
AB039060
BAB68584
AB039061
BAB68585
AB039062
BAB68586
AC027740
M34510
AAA37387
X13987
CAA32166
AK149744
BAE29057
AK151139
BAE30146
AK152427
AK153229
BAE31822
AK156262
BAE33646
AK169880
BAE41432
BC057889
AAH57889
CT010355
CAJ18563
X13333
CAA31710
P10810
NC_005117
NM_021744
NP_068512
NW_001084735
NW_047511
AC_000086
AF087944
AAC35372
AF087943
AAC35371
BC061733
AAH61733
U51804
AAB01154
O88955
Q63691
Source Curated
LocusLink ID 929
12475
60350
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 158120
Alias CD14 antigen
monocyte differentiation antigen CD14
GO ID 0048503
0016019
0006915
0007166
0006954
0006909
0019898
0005886
0006955
0005615
0016020
0046696
Swiss-Prot Accession P08571
Q53XT5
P10810
O88955
Q63691
Unigene ID Hs.163867
Mm.3460