Protein : TLR2
Owner Public
URN urn:agi-llid:7097
Hugo ID 11848
Connectivity 569
Name TLR2
Description toll-like receptor 2
Notes receptor for whom the bell...; involved in the response to bacteria and injury [RGD]
RGD ID 735138
MGI ID 1346060
Cell Localization Plasma membrane
Pathway Toll-Like Receptor pathway
TLR1/2 -> NF-kB signaling pathway
TLR2/4/5/7/9 -> AP-1 signaling pathway
TLR2/6 -> AP-1 signaling pathway
TLR2/6 -> NF-kB signaling pathway
Group Receptors
signal transduction
cell surface receptor linked signal transduction
Toll signaling pathway
induction of apoptosis
positive regulation of tumor necrosis factor-alpha biosynthesis
chloramphenicol transport
inflammatory response
immune response
innate immune response
cell surface
membrane
plasma membrane
integral to membrane
integral to plasma membrane
protein binding
Gram-positive bacterial binding
peptidoglycan binding
lipopolysaccharide receptor activity
receptor activity
transmembrane receptor activity
GenBank ID NC_000004
NM_003264
NP_003255
NT_016354
NW_922217
AC_000047
AC106865
AF051152
AAC34377
AF502291
AAM23001
AK125659
AW614989
BC033756
AAH33756
BI769109
U88878
AAC34133
O60603
NC_000069
NM_011905
NP_036035
NT_039240
NW_000191
NW_001030721
AC_000025
AC133160
AF124741
AAD46481
AF165189
AAD49335
AF185284
AAF04277
AF216289
AAF28345
AK005043
BAB23770
AK154504
BAE32635
AY179346
AAO21125
BC014693
AAH14693
Q9QUN7
NC_005101
NM_198769
NP_942064
NW_001084805
NW_047626
AC_000070
AY151255
AAN86524
AY151256
AAN86525
Source Curated
LocusLink ID 7097
24088
310553
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 603028
246300
Alias TIL4
CD282
toll-like receptor 2
toll/interleukin 1 receptor-like 4
Ly105
toll-like receptor 2 variant 1
toll-like receptor 2 variant 2
GO ID 0051076
0001875
0042834
0005515
0004888
0006917
0006954
0045087
0007165
0009986
0005887
0005886
0004872
0008063
0007166
0042892
0006955
0042535
0016021
0016020
Swiss-Prot Accession O60603
Q9QUN7
Unigene ID Hs.519033
Mm.87596
Rn.46387