Protein : TTRAP
Owner Public
URN urn:agi-llid:51567
Hugo ID 17768
Connectivity 17
Name TTRAP
Description similar to putative TRAF and TNF receptor associated protein
Notes This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
RGD ID 1560342
MGI ID 1860486
Cell Localization Nucleus
Pathway LT-alpha
TNF-alpha
Group Phosphatases
biological_process
cell surface receptor linked signal transduction
cellular_component
nucleus
transcription corepressor activity
endonuclease activity
phosphoric diester hydrolase activity
receptor activity
GenBank ID NC_000006
NM_016614
NP_057698
NT_007592
NW_922984
AC_000049
AL031775
CAA21141
CAD92510
AY613922
AAT09764
AF201687
AAG35600
AF223469
AAF64144
AJ269473
CAB92966
AJ420495
AK002168
BAA92119
BC017553
AAH17553
BC110375
AAI10376
CR592636
CR595644
CR597293
CR601303
CR602029
O95551
NC_000079
NM_019551
NP_062424
NT_039578
NW_000073
NW_001030513
AC_000035
AL589699
CAI26084
AJ251328
CAB92971
AK009089
AK135925
AK137443
AK140178
AK167707
BAE39751
AK216806
AK217996
AK218276
BG070243
BG083167
Q9JJX7
NC_005116
NM_001034947
NP_001030119
NW_001084724
NW_047492
AC_000085
BC101920
AAI01921
Source Curated
LocusLink ID 51567
56196
498749
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 605764
Alias EAP2
AD022
MGC9099
dJ30M3.3
MGC111021
RP1-30M3.3
TRAF and TNF receptor-associated protein
OTTHUMP00000039397
ETS1-associated protein 2
D13Ertd656e
RP23-92G13.1
Traf and Tnf receptor associated protein
LOC498749
MGC124734
hypothetical protein LOC498749
GO ID 0003714
0007166
0005634
0004519
0008081
0004872
0000004
0008372
Swiss-Prot Accession O95551
Q9JJX7
Unigene ID Hs.643501
Mm.19992
Rn.115091