Protein : CDC42
Owner Public
URN urn:agi-llid:998
Hugo ID 1736
Connectivity 1201
Name CDC42
Description cell division cycle 42 homolog (S. cerevisiae)
Notes small GTPase; involved in formation of cellular asymmetry [RGD]
RGD ID 71043
MGI ID 106211
Cell Localization Plasma membrane
Pathway LT-alpha
Jnk-mapk
p38 MAPK
p38 Signaling
TNF-alpha
SAPK-JNK Signaling
EGFR -> AP-1 signaling pathway
NTRK1 -> SMAD3 signaling pathway
NTRKs -> AP-1 signaling pathway
NTRKs -> CREB1 signaling pathway
NTRKs -> ELK1-SRF signaling pathway
NTRKs -> ELK4-SRF signaling pathway
EGFR -> ATF2 signaling pathway
NTRKs -> MYC signaling pathway
NTRKs -> STAT5A signaling pathway
NTRKs -> TP53 signaling pathway
ERBB2/3 -> SP1 signaling pathway
EGFR/ERBB2 -> TP53 signaling pathway
EGFR/ERBB3 -> MEF2A signaling pathway
F2R -> AP-1 signaling pathway
EGFR/ERBB3 -> MEF2C signaling pathway
ENDRA -> AP-1 signaling pathway
RET -> HSF1 signaling pathway
ENDRA -> CREB1 signaling pathway
ENDRB -> AP-1 signaling pathway
F2R -> CREB1 signaling pathway
ENDRB -> CREB1 signaling pathway
ENDRB -> ELK1-SRF signaling pathway
F2R -> ELK1-SRF signaling pathway
ENDRB -> ELK4-SRF signaling pathway
F2R -> ELK4-SRF signaling pathway
F2R -> SP1 signaling pathway
ERBB2 -> ETS2 signaling pathway
ERBB2 -> ETV1 signaling pathway
CD28 -> ATF1 signaling pathway
CD28 -> ATF2 signaling pathway
CD28 -> CREB1 signaling pathway
CD28 -> NF-kB signaling pathway
KDR -> ATF1 signaling pathway
GFRs -> AP-1 signaling pathway
GFRs -> CREB1 signaling pathway
GFRs -> CREBBP signaling pathway
GFRs -> ELK1-SRF signaling pathway
KDR -> ATF2 signaling pathway
GFRs -> ELK4-SRF signaling pathway
KDR -> CREB1 signaling pathway
GFRs -> MYC signaling pathway
GFRs -> NCOR2 signaling pathway
KDR -> ELK1-SRF signaling pathway
KDR -> ELK4-SRF signaling pathway
KDR -> NFATC1 signaling pathway
KIT -> MITF signaling pathway
AGER -> CREB1 signaling pathway
DRD2 -> AP-1 signaling pathway
DRD2 -> CREB1 signaling pathway
DRD2 -> ELK1-SRF signaling pathway
AGER -> SP1 signaling pathway
DRD2 -> ELK4-SRF signaling pathway
Aquaporin
Group Gtp binding proteins
small GTPase mediated signal transduction
Rho protein signal transduction
macrophage differentiation
cell cycle
cell division
G1 phase
regulation of progression through cell cycle
regulation of cell growth
establishment and-or maintenance of cell polarity
filopodium formation
positive regulation of pseudopodium formation
establishment of cell polarity
nuclear migration
actin cytoskeleton organization and biogenesis
actin filament organization
negative regulation of protein complex assembly
positive regulation of phosphoinositide 3-kinase activity
cell projection
intracellular
membrane
filopodium
cytoplasm
plasma membrane
nucleotide binding
protein binding
GTP binding
GTPase activity
GenBank ID NC_000001
NM_001791
NP_001782
NM_044472
NP_426359
NT_004610
NW_927841
AC_000044
NM_001039802
NP_001034891
AL031281
CAB52602
CAD92551
CAI19851
AY673602
AAT70721
CS026525
CAI61729
AF498962
AAM21109
AF498963
AAM21110
AL121734
CAB57325
AL121735
CAB57326
AL121736
CAB57327
AL121737
CAB57328
BC002711
AAH02711
BC003682
AAH03682
BC018266
AAH18266
BC018622
BM684474
BP871988
CR590120
CR595708
CR596776
CR601442
CR623987
M35543
AAA52494
M57298
AAA52592
P50290
P60953
Q5JYX0
Q9UJM0
Q9UJM1
NC_000070
NM_009861
NP_033991
NT_039267
NW_000213
NW_001030750
AC_000026
AL645468
L78075
AAB40051
AK003098
BAB22563
AK051543
BAC34669
AK075567
BAC35825
AK081384
AK144216
BAE25778
AK145659
BAE26572
AK150563
AK151087
BAE30100
AK151726
BAE30644
AK153564
BAE32098
AK154870
BAE32891
AK159470
BAE35111
AK166281
BAE38678
AK167195
BAE39325
AK167400
BAE39489
AK167609
BAE39663
AK168013
BAE40000
AK168076
BAE40049
AK168089
BAE40062
AK168276
BAE40222
AK168503
AK168758
BAE40595
AK168820
BAE40647
AK169122
BAE40902
AK169232
BAE41001
AK169805
BAE41379
AK181967
AK183308
AK208829
AK211726
AK213611
AK218916
BC064792
AAH64792
BF143638
BF467211
BG072071
BG075478
L11318
AAA37410
M79301
AAK14822
U37720
AAC00028
U76960
P60766
Q545V0
NC_005104
NM_171994
NP_741991
NW_001084844
NW_047726
AC_000073
AF205635
AAF15538
AF491841
AAN63806
BC060535
AAH60535
Source Curated
LocusLink ID 998
12540
64465
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 116952
Alias G25K
CDC42Hs
RP1-224A6.5
cell division cycle 42
GTP-binding protein, 25kD
growth-regulating protein
small GTP binding protein
small GTP binding protein CDC42
cell division cycle 42 (GTP binding protein, 25kD)
cell division cycle 42 (GTP-binding protein, 25kD)
dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD))
dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD))
AI747189
AU018915
cell division cycle 42 homolog
GO ID 0005525
0003924
0000166
0005515
0051318
0030036
0007049
0051301
0007163
0030225
0031333
0031274
0001558
0000074
0007264
0005737
0030175
0005622
0016020
0005886
0007266
0007015
0046847
0007097
0043552
0042995
0030010
Swiss-Prot Accession P50290
P60953
Q5JYX0
Q9UJM0
Q9UJM1
P60766
Q545V0
MedScan ID 998
Unigene ID Hs.597524
Mm.1022
Mm.426418
Rn.60067
LocatorString pmquery:aquaporin