Protein : CAV1


Owner	Public
URN	urn:agi-llid:857
Hugo ID	1527
Connectivity	1153
Name	CAV1
Description	caveolin
Notes	structural protein of lipid raft domains in the membrane called caveolae; functions as a cholesterol-binding/shuttling protein [RGD]


RGD ID	2280


MGI ID	102709


Cell Localization	Plasma membrane


Group	inactivation of MAPK activity
	negative regulation of signal transduction
	negative regulation of endothelial cell proliferation
	negative regulation of cell proliferation
	regulation of fatty acid metabolism
	triacylglycerol metabolism
	cholesterol transport
	endocytosis
	transcytosis
	cholesterol homeostasis
	negative regulation of nitric oxide biosynthesis
	protein oligomerization
	protein homooligomerization
	sequestering of lipid
	positive regulation of vasoconstriction
	negative regulation of vasodilation
	membrane
	integral to membrane of membrane fraction
	endoplasmic reticulum
	perinuclear region
	Golgi membrane
	plasma membrane
	integral to membrane
	integral to plasma membrane
	caveola
	caveolar membrane
	lipid raft
	structural molecule activity
	protein binding
	SNARE binding
	syntaxin binding
	cholesterol binding


Source	Curated


OMIM ID	601047


Alias	CAV
	VIP21
	MSTP085
	caveolin 1
	caveolae protein, 22-kD
	caveolin 1, beta isoform
	caveolin 1, alpha isoform
	caveolin 1 caveolae protein, 22kD
	cell growth-inhibiting protein 32
	Cav-1
	caveolin-1
	caveolin, caveolae protein 1
	22 kDa
	caveolin, caveolae protein, 22 kDa
	Cav1
	caveolin caveolae protein 22 kDa


MedScan ID	857


LocatorString	pmquery:aquaporin