Protein : TRADD


Owner	Public
URN	urn:agi-llid:8717
Hugo ID	12030
Connectivity	144
Name	TRADD
Description	TNFRSF1A-associated via death domain
Notes	human homolog plays a role in neurotrophin receptor p75(NTR) mediated anti-apoptotis [RGD]


RGD ID	621313


MGI ID	109200


Pathway	LT-alpha
	FasL
	DR6
	TRAIL
	TNF-alpha signaling
	Death receptor signaling
	p38 Signaling
	TNFR1 signaling
	VEGI
	TNF-alpha
	DR3 and DR4-5 pathways
	NF-kB Signaling
	SAPK-JNK Signaling
	MAPK signaling
	TNFRSF6 -> DDIT3 signaling pathway
	TNFRSF6 -> FOXO3A signaling pathway
	TNFRSF6 -> HSF1 signaling pathway
	TNFRSF6 -> RB1-E2F1 signaling pathway
	TNFRs -> AP-1 signaling pathway
	TNFRs -> ATF2 signaling pathway
	TNFRs -> CREB1 signaling pathway
	TNFRs -> ELK1-SRF signaling pathway
	TNFRs -> ELK4-SRF signaling pathway
	TNFRs -> NF-kB signaling pathway
	NGFR -> AP-1 signaling pathway
	TNFRs -> TP53 signaling pathway
	TNFRSF1A -> AP-1 signaling pathway
	TNFRSF1A -> ATF2 signaling pathway
	TNFRSF1A -> CREB1 signaling pathway
	NGFR -> CEBPB signaling pathway
	TNFRSF1A -> ELK1-SRF signaling pathway
	NGFR -> CREB1 signaling pathway
	NGFR -> ELK1-SRF signaling pathway
	TNFRSF1A -> ELK4-SRF signaling pathway
	NGFR -> ELK4-SRF signaling pathway
	NGFR -> NF-kB signaling pathway
	NGFR -> TP53 signaling pathway
	TNFRSF1A -> TP53 signaling pathway


Group	signal transduction
	positive regulation of I-kappaB kinase-NF-kappaB cascade
	apoptosis
	regulation of apoptosis
	induction of apoptosis
	signal transducer activity
	identical protein binding
	death receptor binding


Source	Curated


OMIM ID	603500


Alias	Hs.89862
	MGC11078
	TNFRSF1A-associated via death domain
	TNFR1-associated death domain protein
	tumor necrosis factor receptor-1-associated protein
	tumor necrosis factor receptor type 1 associated death domain protein
	AA930854
	9130005N23Rik
	TNF receptor 1 associated signal transducer


Swiss-Prot Accession	Q15628
	Q52NZ1