Regulation :

Effect positive
Mechanism unknown
Owner Public
URN urn:agi-Regulation:inout-urn:agi-llid:7186:out-urn:agi-pathway:6ead6b8640d542e01a96faec::positive:unknown
Entities TRAF2 --+> NF kappa B
References 1
Connectivity 2

MedLine Reference 10226064:1233
Sentence Recent data report that following activation of TNF receptors, the adapter molecule TRAF-2 is the bifurcation point that leads to activation either of JNK via RIP or of NF-kappaB via NIK ( 36 ).
Source Curated