Regulation :


Effect	positive
Mechanism	unknown
Owner	Public
URN	urn:agi-Regulation:inout-urn:agi-llid:6654:out-urn:agi-pathway:{93FEEDA4-FB15-46C9-BCA2-076D11090659}::positive:unknown
Entities	SOS1 --+> p40 MAPK
References	1
Connectivity	2


MedLine Reference	9388270:1026
Sentence	Grb2/SOS binding subsequently results in activation of the proto-oncogenes p21 ras and raf and the mitogen-activated protein kinase (MAPK)/extracellular response kinase (ERK) kinase MEK1, which activates the MAP kinases.
Source	Curated