Binding :

Connectivity 2
Owner Public
URN urn:agi-Binding:inout-urn:agi-llid:8772:inout-urn:agi-llid:8737:
Entities FADD ---- RIPK1
References 15
MedLine Reference 9115275:10031
Sentence The death domain motif plays a central role in these interactions, mediating associations between TNFR1, TRADD, MORT1/FADD, and RIP.
Journal J. Biol. Chem
Journal Reference v272 i18 p12069
Journal Link http://www.jbc.org/cgi/content/full/272/18/12069
MedLine Reference 12167698:10163
Sentence TRADD and RIP then interact with FADD to initiate the death pathway through FADD's recruitment of caspase 8 ( 3 , 6 , 14 , 24 , 28 ).
Journal Mol. Cell. Biol
Journal Reference v22 i17 p6034
Journal Link http://mcb.asm.org/cgi/content/full/22/17/6034
MedLine Reference 14701813:10214
Sentence It is highly possible that TRADD, the first adaptor protein to be recruited to TNFRI, and which serves as a platform for RIP, TRAF2, and FADD interacting, is also required.
Journal J. Biol. Chem
Journal Reference v279 i11 p10822
Journal Link http://www.jbc.org/cgi/content/full/279/11/10822
Organism Mus musculus
MedLine Reference 11231290:10024
Journal Eur. J. Biochem
Journal Reference v268 i5 p1382
Journal Link http://www.ejbiochem.org/cgi/content/full/268/5/1382
Organism Mus musculus
MedLine Reference 12167698:1163
Sentence TRADD and RIP then interact with FADD to initiate the death pathway through FADD's recruitment of caspase 8 ( 3 , 6 , 14 , 24 , 28 ).
Journal Mol. Cell. Biol
Journal Reference v22 i17 p6034 (2002)
Journal Link http://mcb.asm.org/cgi/content/full/22/17/6034
Source Curated
MedLine Reference 10092829:1224
Sentence The cytoplasmic death domain of TNFR-I is known to mediate a direct interaction of this receptor with the adapter molecule TRADD, which recruits the signal- transducing molecules FADD, TRAF2, and RIP.
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
MedLine Reference 12351681:1174
Sentence TRADD is a 34 kDa protein that interacts specifically with TNFR1 ( Hsu et al., 1995 ), whereas the 23 kDa FADD ( Boldin et al., 1995a ; Chinnaiyan et al., 1995 ) and the 74 kDa RIP ( Stanger et al., 1995 ) interact with Fas.
Journal PNAS
Journal Reference v96 i3 p1042 (1999)
Journal Link http://www.pnas.org/cgi/content/full/96/3/1042
Organism plant
Source Curated
MedLine Reference 11002422
Source Curated
MedLine Reference 9927690:1028
Source Curated
MedLine Reference 12167697:1018
Source Curated
MedLine Reference 11313468:1275
Source Curated
MedLine Reference 8855284:0
Source Curated
MedLine Reference 9973400:1255
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
MedLine Reference 2389183922
Sentence TRADD is a 34 kDa protein that interacts specifically with TNFR1 ( Hsu et al., 1995 ), whereas the 23 kDa FADD ( Boldin et al., 1995a ; Chinnaiyan et al., 1995 ) and the 74 kDa RIP ( Stanger et al., 1995 ) interact with Fas.
Source Curated