Binding :

Connectivity 2
Owner Public
URN urn:agi-Binding:inout-urn:agi-llid:6654:inout-urn:agi-llid:2885:
Entities Grb2 ---- SOS1
References 1065
MedLine Reference 9383403:2
Sentence The basis of the Grb2-Sos interaction is not fully understood.
MedLine Reference 8816480:8
Sentence These results suggest a role for MAP kinase in the regulation of Grb2-Sos interactions.
MedLine Reference 7542744:1
Sentence Once phosphorylated, Shc binds the Grb2-Sos complex, leading to Ras activation.
MedLine Reference 131101276:11240
MedLine Reference 131102802:11103
MedLine Reference 101001381:11166
Journal Cell
Journal Reference v94 i5 p625
Journal Link http://www.cell.com/cgi/content/full/94/5/625
MedLine Reference 106100150:11098
Journal EMBO
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Journal Link http://www.nature.com/emboj/journal/v23/n7/full/7600151a.html
MedLine Reference 131101642:11161
MedLine Reference 106100249:11167
Journal EMBO
Journal Reference v23 i13 p7600268
Journal Link http://www.nature.com/emboj/journal/v23/n13/full/7600268a.html
MedLine Reference 9820557:10159
Journal J. Immunol
Journal Reference v161 i10 p5755
Journal Link http://www.jimmunol.org/cgi/content/full/161/10/5755
Organism Rattus norvegicus
MedLine Reference 10452997:10203
Journal J. Immunol
Journal Reference v163 i5 p2586
Journal Link http://www.jimmunol.org/cgi/content/full/163/5/2586
Organism Mus musculus
MedLine Reference 9551951:10019
Journal J. Immunol
Journal Reference v160 i1 p24
Journal Link http://www.jimmunol.org/cgi/content/full/160/1/24
Organism Mus musculus
MedLine Reference 11532018:10135
Journal Eur. J. Biochem
Journal Reference v268 i17 p4809
Journal Link http://www.ejbiochem.org/cgi/content/full/268/17/4809
MedLine Reference 14563713:10133
Journal Circulation Res
Journal Reference v93 i10 p925
Journal Link http://circres.ahajournals.org/cgi/content/full/93/10/925
Organism Mus musculus
MedLine Reference 10982386:10196
Journal Mol. Biol. Cell
Journal Reference v11 i9 p2863
Journal Link http://www.molbiolcell.org/cgi/content/full/11/9/2863
Organism Mus musculus
MedLine Reference 9820532:10235
Journal J. Immunol
Journal Reference v161 i10 p5555
Journal Link http://www.jimmunol.org/cgi/content/full/161/10/5555
MedLine Reference 10514505:10276
Journal J. Biol. Chem
Journal Reference v274 i42 p30154
Journal Link http://www.jbc.org/cgi/content/full/274/42/30154
Organism Mus musculus
MedLine Reference 7592693:10029
Journal J. Biol. Chem
Journal Reference v270 i43 p25332
Journal Link http://www.jbc.org/cgi/content/full/270/43/25332
MedLine Reference 8662760:10033
Journal J. Biol. Chem
Journal Reference v271 i22 p13244
Journal Link http://www.jbc.org/cgi/content/full/271/22/13244
Organism Mus musculus
MedLine Reference 11432805:10019
Journal Cell Growth and Diff
Journal Reference v12 i6 p307
Journal Link http://cgd.aacrjournals.org/cgi/content/full/12/6/307
Organism Mus musculus
MedLine Reference 10531323:10298
Journal J. Biol. Chem
Journal Reference v274 i44 p31261
Journal Link http://www.jbc.org/cgi/content/full/274/44/31261
Organism Rattus norvegicus
MedLine Reference 10477763:10256
Journal J. Cell Biol
Journal Reference v146 i5 p1107
Journal Link http://www.jcb.org/cgi/content/full/146/5/1107
MedLine Reference 10454588:10346
Journal Mol. Cell. Biol
Journal Reference v19 i9 p6427
Journal Link http://mcb.asm.org/cgi/content/full/19/9/6427
Organism Mus musculus
MedLine Reference 10499523:10188
Journal Endocrinology
Journal Reference v140 i10 p4659
Journal Link http://endo.endojournals.org/cgi/content/full/140/10/4659
Organism Mus musculus
MedLine Reference 9034330:10195
Journal EMBO
Journal Reference v16 i3 p473
Journal Link http://emboj.oupjournals.org/cgi/content/full/16/3/473
Organism Rattus norvegicus
MedLine Reference 11075717:5
MedLine Reference 11371563:5
Organism Rattus norvegicus
MedLine Reference 10362652:9
MedLine Reference 8649797:3
Organism Rattus norvegicus
MedLine Reference 8663461:6
MedLine Reference 9209406:10
Tissue hematological
MedLine Reference 10477741:5
CellLineName U 937
MedLine Reference 9918770:3
CellType hepatocyte
Organism Rattus norvegicus
MedLine Reference 8670803:5
Organism Mus musculus
MedLine Reference 10209041:5
Organism Mus musculus
CellLineName JURKAT
MedLine Reference 8188688:1
CellType t cell
Organism Rattus norvegicus
MedLine Reference 7898933:2
Organism Mus musculus
MedLine Reference 8479536:1
Organism Mus musculus
MedLine Reference 11466218:10034
Journal Biology of reproduction
Journal Reference v65 i2 p496
Journal Link http://www.biolreprod.org/cgi/content/full/65/2/496
Organism Mus musculus
MedLine Reference 15537634:10033
Journal J. Biol. Chem
Journal Reference v280 i1 p660
Journal Link http://www.jbc.org/cgi/content/full/280/1/660
Organism Mus musculus
MedLine Reference 15143164:10252
Journal Mol. Cell. Biol
Journal Reference v24 i11 p4685
Journal Link http://mcb.asm.org/cgi/content/full/24/11/4685
Organism Mus musculus
MedLine Reference 10514516:10019
Journal J. Biol. Chem
Journal Reference v274 i42 p30236
Journal Link http://www.jbc.org/cgi/content/full/274/42/30236
Organism Mus musculus
MedLine Reference 7650032:10195
Journal J. Biol. Chem
Journal Reference v270 i34 p20135
Journal Link http://www.jbc.org/cgi/content/full/270/34/20135
MedLine Reference 11158334:10026
Journal Mol. Endocrin
Journal Reference v15 i2 p281
Journal Link http://mend.endojournals.org/cgi/content/full/15/2/281
MedLine Reference 8617744:10024
Journal J. Biol. Chem
Journal Reference v271 i9 p4770
Journal Link http://www.jbc.org/cgi/content/full/271/9/4770
MedLine Reference 15888452:10153
Journal J. Biol. Chem
Journal Reference v280 i26 p24524
Journal Link http://www.jbc.org/cgi/content/full/280/26/24524
MedLine Reference 15013949:10233
Journal Cell Phys
Journal Reference v287 i1 p200
Journal Link http://ajpcell.physiology.org/cgi/content/full/287/1/C200
Organism Mus musculus
MedLine Reference 9832564:10203
Journal J. Cell Biol
Journal Reference v143 i5 p1375
Journal Link http://www.jcb.org/cgi/content/full/143/5/1375
MedLine Reference 8995379:10047
Journal J. Biol. Chem
Journal Reference v272 i2 p894
Journal Link http://www.jbc.org/cgi/content/full/272/2/894
MedLine Reference 10805734:10020
Journal Mol. Cell. Biol
Journal Reference v20 i11 p3906
Journal Link http://mcb.asm.org/cgi/content/full/20/11/3906
MedLine Reference 9705962:10017
Journal J. Exp. Med
Journal Reference v188 i4 p791
Journal Link http://www.jem.org/cgi/content/full/188/4/791
MedLine Reference 8910355:10026
Journal J. Biol. Chem
Journal Reference v271 i44 p27652
Journal Link http://www.jbc.org/cgi/content/full/271/44/27652
Organism Mus musculus
MedLine Reference 11283268:10296
Journal Mol. Cell. Biol
Journal Reference v21 i8 p2906
Journal Link http://mcb.asm.org/cgi/content/full/21/8/2906
Organism Mus musculus
MedLine Reference 7538132:10026
Journal J. Biol. Chem
Journal Reference v270 i20 p12085
Journal Link http://www.jbc.org/cgi/content/full/270/20/12085
Organism Mus musculus
MedLine Reference 10359574:10
MedLine Reference 9569023:3
Organism Mus musculus
MedLine Reference 7529871:5
CellType fibroblast
Organism Mus musculus
MedLine Reference 8910422:3
MedLine Reference 9632781:2
Organism Mus musculus
MedLine Reference 10395202:5
CellType b cell
Organism Mus musculus
MedLine Reference 9009162:3
Organism Mus musculus
MedLine Reference 10207047:5
CellType b cell
Organism Mus musculus
MedLine Reference 9087451:1
Organism Mus musculus
MedLine Reference 14679214:4
MedLine Reference 10570290:3
CellLineName U 937
MedLine Reference 7739560:7
Organism Mus musculus
MedLine Reference 9199344:6
Tissue hematological
CellType b cell
Organism Mus musculus
MedLine Reference 9480847:4
Organism Mus musculus
MedLine Reference 8663278:4
CellType MAST
Organism Rattus norvegicus
CellLineName H3
MedLine Reference 7673183:1
Organism Mus musculus
MedLine Reference 12960075:10029
Journal Endocrinology
Journal Reference v144 i12 p5497
Journal Link http://endo.endojournals.org/cgi/content/full/144/12/5497
Organism Mus musculus
MedLine Reference 11884391:10328
Journal J. Biol. Chem
Journal Reference v277 i20 p17638
Journal Link http://www.jbc.org/cgi/content/full/277/20/17638
Organism Mus musculus
MedLine Reference 14963045:10329
Journal J. Biol. Chem
Journal Reference v279 i17 p17205
Journal Link http://www.jbc.org/cgi/content/full/279/17/17205
MedLine Reference 11812785:10306
Journal J. Biol. Chem
Journal Reference v277 i15 p12622
Journal Link http://www.jbc.org/cgi/content/full/277/15/12622
MedLine Reference 8647804:10037
Journal J. Biol. Chem
Journal Reference v271 i21 p12137
Journal Link http://www.jbc.org/cgi/content/full/271/21/12137
MedLine Reference 12538627:10169
Journal Endocrinology
Journal Reference v144 i2 p638
Journal Link http://endo.endojournals.org/cgi/content/full/144/2/638
Organism Rattus norvegicus
MedLine Reference 10744748:10207
Journal J. Biol. Chem
Journal Reference v275 i14 p10545
Journal Link http://www.jbc.org/cgi/content/full/275/14/10545
Organism Mus musculus
MedLine Reference 9236231:10137
Organism Rattus norvegicus
MedLine Reference 9565564:10283
Journal J. Biol. Chem
Journal Reference v273 i19 p11505
Journal Link http://www.jbc.org/cgi/content/full/273/19/11505
MedLine Reference 7537742:10220
Journal J. Biol. Chem
Journal Reference v270 i18 p11017
Journal Link http://www.jbc.org/cgi/content/full/270/18/11017
MedLine Reference 10224278:10170
Journal J. Exp. Med
Journal Reference v189 i9 p1383
Journal Link http://www.jem.org/cgi/content/full/189/9/1383
MedLine Reference 9130441:10101
Journal Circulation Res
Journal Reference v80 i5 p607
Journal Link http://circres.ahajournals.org/cgi/content/full/80/5/607
Organism Mus musculus
MedLine Reference 8663436:10162
Journal J. Biol. Chem
Journal Reference v271 i30 p18122
Journal Link http://www.jbc.org/cgi/content/full/271/30/18122
Organism Mus musculus
MedLine Reference 12055094:10034
Journal Cell Phys
Journal Reference v283 i1 pC251
Journal Link http://ajpcell.physiology.org/cgi/content/full/283/1/C251
Organism Mus musculus
MedLine Reference 10849448:10029
Journal J. Biol. Chem
Journal Reference v275 i24 p18581
Journal Link http://www.jbc.org/cgi/content/full/275/24/18581
MedLine Reference 11825879:10202
Journal Genes & Dev
Journal Reference v16 i3 p388
Journal Link http://www.genesdev.org/cgi/content/full/16/3/388
MedLine Reference 11943676:3
Tissue epithelia
Organism Rattus norvegicus
CellLineName AEC
MedLine Reference 10550332:5
Organism Rattus norvegicus
MedLine Reference 7521298:5
MedLine Reference 7566970:3
Organism Mus musculus
MedLine Reference 8695800:3
MedLine Reference 8810325:5
MedLine Reference 9544989:13
MedLine Reference 9872323:1
Organism Mus musculus
MedLine Reference 7642581:6
CellType t cell
MedLine Reference 8530511:3
Organism Mus musculus
CellLineName B104-1-1
MedLine Reference 7559579:9
Organism Mus musculus
MedLine Reference 9815779:6
Organism Mus musculus
MedLine Reference 7893993:6
MedLine Reference 10395825:1
MedLine Reference 9620547:8
MedLine Reference 8577703:7
CellType t cell
Organism Mus musculus
MedLine Reference 11406576:10017
Journal EMBO
Journal Reference v20 i12 p2995
Journal Link http://emboj.oupjournals.org/cgi/content/full/20/12/2995
Organism Mus musculus
MedLine Reference 10632958:10224
Journal EBM
Journal Reference v223 i1 p22
Journal Link http://www.ebmonline.org/cgi/content/full/223/1/22
MedLine Reference 10652352:10235
Journal J. Biol. Chem
Journal Reference v275 i5 p3568
Journal Link http://www.jbc.org/cgi/content/full/275/5/3568
Organism Rattus norvegicus
MedLine Reference 9447983:10306
Organism Mus musculus
MedLine Reference 10391903:10137
Journal J. Biol. Chem
Journal Reference v274 i28 p19649
Journal Link http://www.jbc.org/cgi/content/full/274/28/19649
MedLine Reference 9478994:10113
Journal J. Biol. Chem
Journal Reference v273 i9 p5343
Journal Link http://www.jbc.org/cgi/content/full/273/9/5343
MedLine Reference 11408601:10133
Journal Mol. Pharm
Journal Reference v60 i1 p63
Journal Link http://molpharm.aspetjournals.org/cgi/content/full/60/1/63
Organism Rattus norvegicus
MedLine Reference 11352907:10255
Journal J. Biol. Chem
Journal Reference v276 i28 p26622
Journal Link http://www.jbc.org/cgi/content/full/276/28/26622
Organism Rattus norvegicus
MedLine Reference 10385399:10273
Journal Endocrinology
Journal Reference v140 i7 p3073
Journal Link http://endo.endojournals.org/cgi/content/full/140/7/3073
Organism Rattus norvegicus
MedLine Reference 11884620:10165
Journal Mol. Cell. Biol
Journal Reference v22 i7 p2375
Journal Link http://mcb.asm.org/cgi/content/full/22/7/2375
Organism Rattus norvegicus
MedLine Reference 10903746:10244
Journal J. Immunol
Journal Reference v165 i3 p1417
Journal Link http://www.jimmunol.org/cgi/content/full/165/3/1417
Organism Mus musculus
MedLine Reference 15899849:10334
Journal Mol. Cell. Biol
Journal Reference v25 i11 p4426
Journal Link http://mcb.asm.org/cgi/content/full/25/11/4426
MedLine Reference 12093866:10270
Journal J. Exp. Med
Journal Reference v196 i1 p1
Journal Link http://www.jem.org/cgi/content/full/196/1/1
Organism Mus musculus
MedLine Reference 10629055:10284
Journal Mol. Cell. Biol
Journal Reference v20 i3 p979
Journal Link http://mcb.asm.org/cgi/content/full/20/3/979
MedLine Reference 9614103:10033
Organism Rattus norvegicus
MedLine Reference 10488105:10029
Journal J. Biol. Chem
Journal Reference v274 i39 p27651
Journal Link http://www.jbc.org/cgi/content/full/274/39/27651
Organism Mus musculus
MedLine Reference 10373477:3
MedLine Reference 7664271:5
CellLineName MCF7
MedLine Reference 16436051:6
MedLine Reference 8063737:10
Organism Mus musculus
CellLineName Rat1
MedLine Reference 8765045:5
CellType b cell
Organism Mus musculus
MedLine Reference 9872927:5
Organism Mus musculus
CellLineName ER22
MedLine Reference 7829473:3
CellType adipocyte
Organism Mus musculus
CellLineName 3T3 L1
MedLine Reference 7518772:10
Organism Mus musculus
CellLineName NIH 3T3
MedLine Reference 8626525:1
MedLine Reference 8697095:6
Organ liver
Organism Mus musculus
MedLine Reference 7799946:0
Organism Mus musculus
MedLine Reference 7568223:5
CellType t cell
MedLine Reference 8649846:5
Organism Mus musculus
MedLine Reference 8545109:1
Organism Mus musculus
MedLine Reference 12519863:4
MedLine Reference 8626428:8
CellType adipocyte
Organism Mus musculus
CellLineName CHO
MedLine Reference 11390647:10053
Journal Mol. Cell. Biol
Journal Reference v21 i13 p4177
Journal Link http://mcb.asm.org/cgi/content/full/21/13/4177
MedLine Reference 8940158:10127
Journal J. Biol. Chem
Journal Reference v271 i49 p31458
Journal Link http://www.jbc.org/cgi/content/full/271/49/31458
Organism Mus musculus
MedLine Reference 10377388:10138
Journal PNAS
Journal Reference v96 i13 p7178
Journal Link http://www.pnas.org/cgi/content/full/96/13/7178
Organism Rattus norvegicus
MedLine Reference 10493769:10032
Organism Rattus norvegicus
MedLine Reference 10464302:10175
Journal J. Biol. Chem
Journal Reference v274 i36 p25659
Journal Link http://www.jbc.org/cgi/content/full/274/36/25659
Organism Rattus norvegicus
MedLine Reference 9447970:10283
Organism Mus musculus
MedLine Reference 11287318:10288
Journal Cell Phys
Journal Reference v280 i5 pC1066
Journal Link http://ajpcell.physiology.org/cgi/content/full/280/5/C1066
Organism Mus musculus
MedLine Reference 9549755:10368
Journal Pharm. Rev
Journal Reference v50 i1 p1
Journal Link http://pharmrev.aspetjournals.org/cgi/content/full/50/1/1
MedLine Reference 9618511:10035
Journal PNAS
Journal Reference v95 i12 p6903
Journal Link http://www.pnas.org/cgi/content/full/95/12/6903
MedLine Reference 9813041:10025
Organism Mus musculus
MedLine Reference 8662827:10179
Journal J. Biol. Chem
Journal Reference v271 i24 p14610
Journal Link http://www.jbc.org/cgi/content/full/271/24/14610
Organism Mus musculus
MedLine Reference 8663276:10228
Journal J. Biol. Chem
Journal Reference v271 i29 p17021
Journal Link http://www.jbc.org/cgi/content/full/271/29/17021
MedLine Reference 11850215:15
Organism Mus musculus
MedLine Reference 7721878:10041
Journal J. Biol. Chem
Journal Reference v270 i16 p9500
Journal Link http://www.jbc.org/cgi/content/full/270/16/9500
Organism Rattus norvegicus
MedLine Reference 15494547:10284
Journal Renal Phys
Journal Reference v288 i2 p334
Journal Link http://ajprenal.physiology.org/cgi/content/full/288/2/F334
Organism Mus musculus
MedLine Reference 10864922:10351
Journal J. Biol. Chem
Journal Reference v275 i39 p30029
Journal Link http://www.jbc.org/cgi/content/full/275/39/30029
MedLine Reference 16125055:11
CellType Myeloid Progenitor
Organism Mus musculus
MedLine Reference 9856979:4
CellLineName RTE
MedLine Reference 7513258:2
MedLine Reference 11002419:5
Tissue neuroectoderm
MedLine Reference 8617726:0
Organism Mus musculus
CellLineName AB
MedLine Reference 10777511:8
CellLineName MCF7
MedLine Reference 12112020:9
Organism Rattus norvegicus
CellLineName HTC-IR
MedLine Reference 8950972:2
Organism Mus musculus
MedLine Reference 14687662:4
CellType adipocyte
Organism Mus musculus
CellLineName 3T3 L1
MedLine Reference 10208427:4
CellType fibroblast
Organism Mus musculus
MedLine Reference 8552085:8
MedLine Reference 7651538:5
MedLine Reference 7970720:8
MedLine Reference 15481817:3
MedLine Reference 15272025:6
Organism Mus musculus
MedLine Reference 8900204:11
Organ pancreas
Organism Mus musculus
MedLine Reference 14576154:10193
Journal J. Biol. Chem
Journal Reference v279 i5 p3202
Journal Link http://www.jbc.org/cgi/content/full/279/5/3202
Organism Mus musculus
MedLine Reference 12620895:10053
Journal Cell Phys
Journal Reference v284 i4 pC988
Journal Link http://ajpcell.physiology.org/cgi/content/full/284/4/C988
Organism Rattus norvegicus
MedLine Reference 12114513:10316
Journal J. Biol. Chem
Journal Reference v277 i39 p36509
Journal Link http://www.jbc.org/cgi/content/full/277/39/36509
Organism Mus musculus
MedLine Reference 11502202:10156
Journal Eur. J. Biochem
Journal Reference v268 i16 p4423
Journal Link http://www.ejbiochem.org/cgi/content/full/268/16/4423
Organism Rattus norvegicus
MedLine Reference 11159826:10154
Journal Endocrinology
Journal Reference v142 i2 p564
Journal Link http://endo.endojournals.org/cgi/content/full/142/2/564
Organism Mus musculus
MedLine Reference 9528944:10041
Journal Endocrinology
Journal Reference v139 i4 p1638
Journal Link http://endo.endojournals.org/cgi/content/full/139/4/1638
Organism Mus musculus
MedLine Reference 11117534:10246
Journal Mol. Endocrin
Journal Reference v14 i12 p2054
Journal Link http://mend.endojournals.org/cgi/content/full/14/12/2054
Organism Mus musculus
MedLine Reference 11406493:10220
Journal Heart Circul
Journal Reference v281 i1 pH266
Journal Link http://ajpheart.physiology.org/cgi/content/full/281/1/H266
MedLine Reference 9819387:10386
Organism Mus musculus
MedLine Reference 8550624:10023
Journal J. Biol. Chem
Journal Reference v271 i1 p588
Journal Link http://www.jbc.org/cgi/content/full/271/1/588
Organism Mus musculus
</
MedLine Reference 8910399:10218
Journal J. Biol. Chem
Journal Reference v271 i44 p27962
Journal Link http://www.jbc.org/cgi/content/full/271/44/27962
Organism Mus musculus