Binding :


Connectivity	2
Owner	Public
URN	urn:agi-Binding:inout-urn:agi-llid:4087:inout-urn:agi-llid:2033:
Entities	EP300 ---- MADH2
References	51


MedLine Reference	9813111:9
Sentence	p300 interacted with Smad2 and Smad3 in a ligand-dependent manner, and enhanced the transactivation by Smads.


MedLine Reference	14520013:4
Sentence	The physical interaction of p300 with Smad2/3 was examined by immunoprecipitation followed by Western blotting.
Tissue	mesangia
Organism	Mus musculus


MedLine Reference	12097320:10131
Sentence	Tax inhibits the interaction of Smad2 with p300.
Journal	J. Biol. Chem
Journal Reference	v277 i37 p33766
Journal Link	http://www.jbc.org/cgi/content/full/277/37/33766


MedLine Reference	101001700:11219
Journal	Cell
Journal Reference	v97 i1 p29.1
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.1


MedLine Reference	101001701:11219
Journal	Cell
Journal Reference	v97 i1 p29.2
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.2


MedLine Reference	101001702:11219
Journal	Cell
Journal Reference	v97 i1 p29
Journal Link	http://www.cell.com/cgi/content/full/97/1/29


MedLine Reference	16322555:10392
Journal	Genes & Dev
Journal Reference	v19 i23 p2783
Journal Link	http://www.genesdev.org/cgi/content/full/19/23/2783


MedLine Reference	12904571:10024
Journal	PNAS
Journal Reference	v100 i17 p9791
Journal Link	http://www.pnas.org/cgi/content/full/100/17/9791
Organism	Mus musculus


MedLine Reference	9843571:10179
Journal	Mol. Biol. Cell
Journal Reference	v9 i12 p3309
Journal Link	http://www.molbiolcell.org/cgi/content/full/9/12/3309


MedLine Reference	10085121:10221
Journal	J. Biol. Chem
Journal Reference	v274 i13 p8797
Journal Link	http://www.jbc.org/cgi/content/full/274/13/8797


MedLine Reference	14612439:10025
Journal	J. Biol. Chem
Journal Reference	v279 i4 p2666
Journal Link	http://www.jbc.org/cgi/content/full/279/4/2666


MedLine Reference	11371641:10110
Journal	PNAS
Journal Reference	v98 i11 p6198
Journal Link	http://www.pnas.org/cgi/content/full/98/11/6198
Organism	Mus musculus


MedLine Reference	15576380:10307
Journal	J. Biol. Chem
Journal Reference	v280 i7 p6204
Journal Link	http://www.jbc.org/cgi/content/full/280/7/6204
Organism	Mus musculus


MedLine Reference	15623506:10217
Journal	J. Biol. Chem
Journal Reference	v280 i9 p8343
Journal Link	http://www.jbc.org/cgi/content/full/280/9/8343


MedLine Reference	9679056:10064
Journal	Genes & Dev
Journal Reference	v12 i14 p2114
Journal Link	http://www.genesdev.org/cgi/content/full/12/14/2114


MedLine Reference	9679056
Sentence	p300 interacts with Smad2. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human Smad2
Source	Curated


MedLine Reference	11013220:1304
Sentence	CBP/p300 has been shown to interact directly with the C-termini of Smad2 or Smad3, and to serve as coactivator for Smad-mediated transcription ( Feng et al ., 1998 ; Janknecht et al ., 1998 ; Nishihara et al ., 1998 ; Pouponnot et al ., 1998 ; Shen et al ., 1998 ; Topper et al ., 1998 ).
Source	Curated


MedLine Reference	14625694:4
Organ	lung
Organism	rat
Source	Curated


MedLine Reference	12904571:1024
Journal	PNAS
Journal Reference	v100 i17 p9791 (1996)
Journal Link	http://www.pnas.org/cgi/content/full/100/17/9791
Organism	mouse
Source	Curated


MedLine Reference	11371641:1109
Journal	PNAS
Journal Reference	v98 i11 p6198 (2001)
Journal Link	http://www.pnas.org/cgi/content/full/98/11/6198
Source	Curated
CellLineName	COS-7


MedLine Reference	11359897:1036
Journal	Mol. Cell. Biol
Journal Reference	v21 i12 p3901 (2001)
Journal Link	http://mcb.asm.org/cgi/content/full/21/12/3901
Organism	mouse
Source	Curated


MedLine Reference	9843571:1179
Journal	Mol. Biol. Cell
Journal Reference	v9 i12 p3309 (1998)
Journal Link	http://www.molbiolcell.org/cgi/content/full/9/12/3309
Source	Curated


MedLine Reference	12097320:1130
Journal	J. Biol. Chem
Journal Reference	v277 i37 p33766 (2002)
Journal Link	http://www.jbc.org/cgi/content/full/277/37/33766
Source	Curated
CellLineName	HepG 2


MedLine Reference	10085121:1223
Tissue	endothelial
Journal	J. Biol. Chem
Journal Reference	v274 i13 p8797 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/13/8797
Organism	bovine
Source	Curated


MedLine Reference	9679056:1064
Journal	Genes & Dev
Journal Reference	v12 i14 p2114 (1998)
Journal Link	http://www.genesdev.org/cgi/content/full/12/14/2114
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29
Source	Curated
CellLineName	293T


Journal	Cell
Journal Reference	v97 i1 p29 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29
Source	Curated
CellLineName	293T


Journal	Cell
Journal Reference	v97 i1 p29.2 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.2
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29.2 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.2
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29.2 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.2
Source	Curated
CellLineName	293T


Journal	Cell
Journal Reference	v97 i1 p29.2 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.2
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29.2 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.2
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29.1 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.1
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29.1 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.1
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29.2 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.2
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29.2 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.2
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29.1 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.1
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29
Source	Curated
CellLineName	293T


Journal	Cell
Journal Reference	v97 i1 p29 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29
Source	Curated
CellLineName	293T


Journal	Cell
Journal Reference	v97 i1 p29.2 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.2
Source	Curated
CellLineName	293T


Journal	Cell
Journal Reference	v97 i1 p29.2 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.2
Source	Curated
CellLineName	293T


Journal	Cell
Journal Reference	v97 i1 p29.1 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.1
Source	Curated
CellLineName	293T


Journal	Cell
Journal Reference	v97 i1 p29.1 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.1
Source	Curated
CellLineName	293T


MedLine Reference	11264182
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29
Source	Curated


Journal	Cell
Journal Reference	v97 i1 p29 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29
Source	Curated


MedLine Reference	3101245026
Sentence	The interaction of Smad2 with either HDACs (via TGIF) or p300/CBP suggests that Smad complexes regulate transcription in part by remodeling of the chromatin template.
Journal	Cell
Journal Reference	v97 i1 p29.1 (1999)
Journal Link	http://www.cell.com/cgi/content/full/97/1/29.1
Source	Curated