Protein : RASA1

Owner Public
URN urn:agi-llid:5921
Hugo ID 9871
Connectivity 261
Name RASA1
Description RAS p21 protein activator 1
Notes may play a role in Ras GTPase mediated signal transduction; may be involved in cell proliferation and cell migration [RGD]

RGD ID 3537

MGI ID 97860

Pathway EPHB3
EPHB2
Insulin pathway
EGF signaling
PDGFRB
PDGF signaling
G-protein Coupled Receptor signaling
EGF

Group Gtpase regulators
Ph
Sh2
cell adhesion
negative regulation of cell-matrix adhesion
negative regulation of cell adhesion
intracellular signaling cascade
regulation of small GTPase mediated signal transduction
vasculogenesis
negative regulation of neuron apoptosis
positive regulation of anti-apoptosis
cytokinesis
regulation of cell shape
actin cytoskeleton organization and biogenesis
regulation of actin filament polymerization
regulation of RNA metabolism
embryonic development
intracellular
cytoplasm
protein binding
receptor binding
GTPase binding
GTPase activator activity
Ras GTPase activator activity
potassium channel inhibitor activity

GenBank ID NC_000005
NM_002890
NP_002881
NM_022650
NP_072179
NT_006713
NW_922729
AC_000048
AC010410
AC018754
AC035142
AC126776
AB209106
BAD92343
BC020761
BC033015
AAH33015
BC054891
AAH54891
BC070063
BC107870
CR749722
CAH18488
M23379
AAA52517
M23612
AAA35865
P20936
Q59GK3
Q68CU6
Q7Z4M2
NC_000079
NM_145452
NP_663427
NT_039589
NW_000084
NW_001030529
AC_000035
AC127316
AA124924
AA881632
AK042801
AK046620
AK133354
BAE21614
AK161497
BAE36423
AW124937
BC013637
AAH13637
BC065082
BG074050
BG074180
BG086763
NC_005101
NM_013135
NP_037267
NW_001084795
NW_047616
AC_000070
L13151
AAA16319
P50904

Source Curated

LocusLink ID 5921
218397
25676

Organism Homo sapiens
Mus musculus
Rattus norvegicus

OMIM ID 139150
608354
608355

Alias GAP
PKWS
RASA
CMAVM
CM-AVM
RASGAP
p120GAP
DKFZp434N071
RAS p21 protein activator 1
GTPase activating protein
triphosphatase-activating protein
MGC7759
p120-rasGAP
GTPase-activating protein
GAPX

GO ID 0051020
0005099
0019870
0005102
0030036
0007155
0000910
0009790
0007242
0007162
0001953
0043524
0045768
0051252
0030833
0008360
0051056
0001570
0005737
0005622
0005096
0005515

Swiss-Prot Accession P20936
Q59GK3
Q68CU6
Q7Z4M2
P50904

Unigene ID Hs.553501
Mm.259653
Rn.162548