Binding :

Connectivity 2
Owner Public
URN urn:agi-Binding:inout-urn:agi-llid:6464:inout-urn:agi-llid:2885:
Entities Grb2 ---- SHC1
References 1250
MedLine Reference 8752899:5
Sentence Y577 is also required for association of Shc with GRB2.
Organism Mus musculus
MedLine Reference 7898932:7
Sentence These effects require the association of Shc with Grb2.
MedLine Reference 9446569:10
Sentence UTP also promoted the association of Shc with Grb2.
Organism Rattus norvegicus
MedLine Reference 15364923:10338
Journal J. Biol. Chem
Journal Reference v279 i46 p47871
Journal Link http://www.jbc.org/cgi/content/full/279/46/47871
Organism Mus musculus
MedLine Reference 10900220:10217
Journal JPET
Journal Reference v294 i2 p466
Journal Link http://jpet.aspetjournals.org/cgi/content/full/294/2/466
MedLine Reference 9415395:10142
Journal Mol. Endocrin
Journal Reference v11 i13 p1899
Journal Link http://mend.endojournals.org/cgi/content/full/11/13/1899
Organism Rattus norvegicus
MedLine Reference 11884411:10232
Journal J. Biol. Chem
Journal Reference v277 i21 p19206
Journal Link http://www.jbc.org/cgi/content/full/277/21/19206
Organism Mus musculus
MedLine Reference 11353842:10204
Journal PNAS
Journal Reference v98 i11 p6074
Journal Link http://www.pnas.org/cgi/content/full/98/11/6074
Organism Mus musculus
MedLine Reference 9092520:10203
Journal J. Biol. Chem
Journal Reference v272 i15 p9847
Journal Link http://www.jbc.org/cgi/content/full/272/15/9847
Organism Rattus norvegicus
MedLine Reference 7537740:10028
Journal J. Biol. Chem
Journal Reference v270 i18 p10800
Journal Link http://www.jbc.org/cgi/content/full/270/18/10800
MedLine Reference 9099726:10025
Journal J. Biol. Chem
Journal Reference v272 i16 p10751
Journal Link http://www.jbc.org/cgi/content/full/272/16/10751
Organism Rattus norvegicus
MedLine Reference 9374504:10155
Journal J. Biol. Chem
Journal Reference v272 i48 p30208
Journal Link http://www.jbc.org/cgi/content/full/272/48/30208
MedLine Reference 12529254:10214
Journal Cell Phys
Journal Reference v284 i2 pC571
Journal Link http://ajpcell.physiology.org/cgi/content/full/284/2/C571
Organism Rattus norvegicus
MedLine Reference 11134016:10287
Journal J. Biol. Chem
Journal Reference v276 i13 p9733
Journal Link http://www.jbc.org/cgi/content/full/276/13/9733
Organism Mus musculus
MedLine Reference 15082760:10022
Journal Mol. Cell. Biol
Journal Reference v24 i9 p3633
Journal Link http://mcb.asm.org/cgi/content/full/24/9/3633
Organism Rattus norvegicus
MedLine Reference 12058069:10020
Journal Mol. Biol. Cell
Journal Reference v13 i6 p2057
Journal Link http://www.molbiolcell.org/cgi/content/full/13/6/2057
Organism Mus musculus
MedLine Reference 9171350:10051
Journal EMBO
Journal Reference v16 i9 p2365
Journal Link http://emboj.oupjournals.org/cgi/content/full/16/9/2365
Organism Mus musculus
MedLine Reference 7744881:10346
Journal J. Biol. Chem
Journal Reference v270 i20 p12286
Journal Link http://www.jbc.org/cgi/content/full/270/20/12286
Organism Mus musculus
MedLine Reference 14660677:10037
Journal J. Biol. Chem
Journal Reference v279 i7 p5520
Journal Link http://www.jbc.org/cgi/content/full/279/7/5520
Organism Mus musculus
MedLine Reference 14557262:10054
Journal J. Biol. Chem
Journal Reference v279 i1 p326
Journal Link http://www.jbc.org/cgi/content/full/279/1/326
MedLine Reference 7642641:10123
Journal J. Biol. Chem
Journal Reference v270 i33 p19557
Journal Link http://www.jbc.org/cgi/content/full/270/33/19557
Organism Mus musculus
MedLine Reference 8978277:10097
Journal Blood
Journal Reference v89 i1 p55
Journal Link http://www.bloodjournal.org/cgi/content/full/89/1/55
Organism Mus musculus
MedLine Reference 15210794:10398
Journal J. Immunol
Journal Reference v173 i1 p360
Journal Link http://www.jimmunol.org/cgi/content/full/173/1/360
Organism Mus musculus
MedLine Reference 10465268:10112
Journal Endocrinology
Journal Reference v140 i9 p3992
Journal Link http://endo.endojournals.org/cgi/content/full/140/9/3992
Organism Mus musculus
MedLine Reference 10777525:10264
Journal J. Biol. Chem
Journal Reference v275 i17 p12416
Journal Link http://www.jbc.org/cgi/content/full/275/17/12416
MedLine Reference 12917446:10232
Journal J. Biol. Chem
Journal Reference v278 i43 p41646
Journal Link http://www.jbc.org/cgi/content/full/278/43/41646
Organism Mus musculus
MedLine Reference 11278982:10146
Journal J. Biol. Chem
Journal Reference v276 i19 p16045
Journal Link http://www.jbc.org/cgi/content/full/276/19/16045
MedLine Reference 8621475:10096
Journal J. Biol. Chem
Journal Reference v271 i15 p8529
Journal Link http://www.jbc.org/cgi/content/full/271/15/8529
MedLine Reference 7538132:10127
Journal J. Biol. Chem
Journal Reference v270 i20 p12085
Journal Link http://www.jbc.org/cgi/content/full/270/20/12085
Organism Mus musculus
MedLine Reference 12379659:10157
Journal J. Biol. Chem
Journal Reference v278 i2 p1108
Journal Link http://www.jbc.org/cgi/content/full/278/2/1108
Organism Rattus norvegicus
MedLine Reference 9834070:10034
Journal J. Immunol
Journal Reference v161 i11 p5901
Journal Link http://www.jimmunol.org/cgi/content/full/161/11/5901
MedLine Reference 9867813:10161
Organism Rattus norvegicus
MedLine Reference 9611107:10252
Journal Cell Phys
Journal Reference v274 i6 pC1429
Journal Link http://ajpcell.physiology.org/cgi/content/full/274/6/C1429
MedLine Reference 9886807:10124
Journal Endocrinology
Journal Reference v140 i1 p55
Journal Link http://endo.endojournals.org/cgi/content/full/140/1/55
Organism Rattus norvegicus
MedLine Reference 11562449:10205
Journal Mol. Pharm
Journal Reference v60 i4 p857
Journal Link http://molpharm.aspetjournals.org/cgi/content/full/60/4/857
Organism Mus musculus
MedLine Reference 16146636:6
Organism Mus musculus
MedLine Reference 8605873:5
CellType fibroblast
MedLine Reference 9607818:1
Organism Rattus norvegicus
MedLine Reference 9651378:6
CellLineName INS-1 cell
MedLine Reference 10764799:5
CellLineName HepG 2
MedLine Reference 7798267:5
Organism Rattus norvegicus
MedLine Reference 7542744:1
MedLine Reference 11075717:6
MedLine Reference 8051109:1
Organism Mus musculus
MedLine Reference 7498649:7
Organ gastric
Organism Rattus norvegicus
MedLine Reference 8063737:2
Organism Mus musculus
MedLine Reference 9126968:9
MedLine Reference 14971902:3
Organism Mus musculus
MedLine Reference 8621421:10070
Journal J. Biol. Chem
Journal Reference v271 i10 p5603
Journal Link http://www.jbc.org/cgi/content/full/271/10/5603
Organism Mus musculus
MedLine Reference 10835099:10550
Journal Pharm. Rev
Journal Reference v52 i2 p179
Journal Link http://pharmrev.aspetjournals.org/cgi/content/full/52/2/179
MedLine Reference 12686619:10032
Journal Mol. Biol. Cell
Journal Reference v14 i4 p1691
Journal Link http://www.molbiolcell.org/cgi/content/full/14/4/1691
MedLine Reference 10766863:10224
Journal J. Biol. Chem
Journal Reference v275 i16 p12251
Journal Link http://www.jbc.org/cgi/content/full/275/16/12251
Organism Mus musculus
MedLine Reference 9013586:10029
Journal J. Biol. Chem
Journal Reference v272 i6 p3423
Journal Link http://www.jbc.org/cgi/content/full/272/6/3423
Organism Rattus norvegicus
MedLine Reference 9647866:10805
Journal Pharm. Rev
Journal Reference v50 i2 p197
Journal Link http://pharmrev.aspetjournals.org/cgi/content/full/50/2/197
MedLine Reference 10846186:10238
Journal J. Biol. Chem
Journal Reference v275 i34 p26545
Journal Link http://www.jbc.org/cgi/content/full/275/34/26545
MedLine Reference 12118065:10221
Journal Cell Sci
Journal Reference v115 i15 p3093
Journal Link http://jcs.biologists.org/cgi/content/full/115/15/3093
Organism Mus musculus
MedLine Reference 15192046:10308
Journal Endocrinology
Journal Reference v145 i9 p4232
Journal Link http://endo.endojournals.org/cgi/content/full/145/9/4232
MedLine Reference 8702915:10038
Journal J. Biol. Chem
Journal Reference v271 i35 p21353
Journal Link http://www.jbc.org/cgi/content/full/271/35/21353
Organism Mus musculus
MedLine Reference 9671791:10024
Journal PNAS
Journal Reference v95 i15 p8985
Journal Link http://www.pnas.org/cgi/content/full/95/15/8985
Organism Rattus norvegicus
MedLine Reference 14613932:10165
Journal J. Biol. Chem
Journal Reference v279 i6 p4657
Journal Link http://www.jbc.org/cgi/content/full/279/6/4657
MedLine Reference 16002410:10282
Journal J. Biol. Chem
Journal Reference v280 i36 p31428
Journal Link http://www.jbc.org/cgi/content/full/280/36/31428
MedLine Reference 11196191:10182
Journal Cancer Res
Journal Reference v61 i1 p383
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/61/1/383
MedLine Reference 12642580:10245
Journal J. Biol. Chem
Journal Reference v278 i21 p19118
Journal Link http://www.jbc.org/cgi/content/full/278/21/19118
Organism Mus musculus
MedLine Reference 15271882:10313
Journal Endocrinology
Journal Reference v145 i11 p4976
Journal Link http://endo.endojournals.org/cgi/content/full/145/11/4976
MedLine Reference 16581764:10177
Journal Mol. Cell. Biol
Journal Reference v26 i8 p2877
Journal Link http://mcb.asm.org/cgi/content/full/26/8/2877
MedLine Reference 11438521:10134
Journal J. Biol. Chem
Journal Reference v276 i35 p32779
Journal Link http://www.jbc.org/cgi/content/full/276/35/32779
Organism Rattus norvegicus
MedLine Reference 14644750:10347
Journal Renal Phys
Journal Reference v286 i3 pF466
Journal Link http://ajprenal.physiology.org/cgi/content/full/286/3/F466
Organism Rattus norvegicus
MedLine Reference 15855657:10349
Journal Renal Phys
Journal Reference v289 i3 p593
Journal Link http://ajprenal.physiology.org/cgi/content/full/289/3/F593
Organism Rattus norvegicus
MedLine Reference 11934884:10146
Journal J. Biol. Chem
Journal Reference v277 i23 p20618
Journal Link http://www.jbc.org/cgi/content/full/277/23/20618
Organism Mus musculus
MedLine Reference 10644676:10267
Journal J. Biol. Chem
Journal Reference v275 i4 p2281
Journal Link http://www.jbc.org/cgi/content/full/275/4/2281
Organism Mus musculus
MedLine Reference 10319320:10203
Journal Mol. Endocrin
Journal Reference v13 i5 p692
Journal Link http://mend.endojournals.org/cgi/content/full/13/5/692
MedLine Reference 8662827:10188
Journal J. Biol. Chem
Journal Reference v271 i24 p14610
Journal Link http://www.jbc.org/cgi/content/full/271/24/14610
Organism Mus musculus
MedLine Reference 10477722:10032
Journal Blood
Journal Reference v94 i6 p1933
Journal Link http://www.bloodjournal.org/cgi/content/full/94/6/1933
Organism Mus musculus
MedLine Reference 10984494:10186
Journal J. Biol. Chem
Journal Reference v275 i51 p40301
Journal Link http://www.jbc.org/cgi/content/full/275/51/40301
Organism Rattus norvegicus
MedLine Reference 12052829:10197
Journal J. Biol. Chem
Journal Reference v277 i33 p30144
Journal Link http://www.jbc.org/cgi/content/full/277/33/30144
Organism Mus musculus
MedLine Reference 9013643:10211
Journal J. Biol. Chem
Journal Reference v272 i6 p3838
Journal Link http://www.jbc.org/cgi/content/full/272/6/3838
Organism Mus musculus
MedLine Reference 9763606:10111
Journal J. Exp. Med
Journal Reference v188 i7 p1267
Journal Link http://www.jem.org/cgi/content/full/188/7/1267
Organism Mus musculus
MedLine Reference 12734402:10239
Journal Cell Sci
Journal Reference v116 i12 p2585
Journal Link http://jcs.biologists.org/cgi/content/full/116/12/2585
MedLine Reference 9345034:10128
Journal Blood
Journal Reference v90 i9 p3507
Journal Link http://www.bloodjournal.org/cgi/content/full/90/9/3507
MedLine Reference 7721878:10204
Journal J. Biol. Chem
Journal Reference v270 i16 p9500
Journal Link http://www.jbc.org/cgi/content/full/270/16/9500
Organism Rattus norvegicus
MedLine Reference 8939605:9
Organism Mus musculus
MedLine Reference 9642236:7
CellType pre B
Organism Mus musculus
CellLineName BaF3
MedLine Reference 7650032:5
Organ brain
CellType pre B
MedLine Reference 7543044:5
CellLineName CHO
MedLine Reference 12790774:8
CellLineName LTED
MedLine Reference 10362652:8
MedLine Reference 16113100:8
CellLineName LTED
MedLine Reference 11444425:4
Organ liver
Tissue muscle
Organism Mus musculus
MedLine Reference 9486662:5
Organ heart
CellType fibroblast
Organism Mus musculus
MedLine Reference 16024245:7
Organism Mus musculus
CellLineName LTED
MedLine Reference 10471533:3
Organism Mus musculus
MedLine Reference 16126371:2
CellLineName HEK 293
MedLine Reference 8144662:5
CellType fibroblast
Organism Rattus norvegicus
CellLineName Rat1
MedLine Reference 12160999:8
Organ breast
MedLine Reference 7898933:2
Organism Mus musculus
MedLine Reference 7535773:10
Organism Mus musculus
CellLineName CHO
MedLine Reference 9862703:10273
Journal J. Immunol
Journal Reference v161 i12 p6733
Journal Link http://www.jimmunol.org/cgi/content/full/161/12/6733
Organism Rattus norvegicus
MedLine Reference 15528274:10174
Journal Mol. Endocrin
Journal Reference v19 i1 p1
Journal Link http://mend.endojournals.org/cgi/content/full/19/1/1
Organism Mus musculus
MedLine Reference 8955163:10171
Journal J. Biol. Chem
Journal Reference v271 i51 p33141
Journal Link http://www.jbc.org/cgi/content/full/271/51/33141
Organism Mus musculus
MedLine Reference 10702272:10081
Journal J. Biol. Chem
Journal Reference v275 i10 p7066
Journal Link http://www.jbc.org/cgi/content/full/275/10/7066
Organism Rattus norvegicus
MedLine Reference 11390373:10346
Journal J. Biol. Chem
Journal Reference v276 i33 p31422
Journal Link http://www.jbc.org/cgi/content/full/276/33/31422
MedLine Reference 12417588:10158
Journal J. Biol. Chem
Journal Reference v278 i5 p2896
Journal Link http://www.jbc.org/cgi/content/full/278/5/2896
Organism Mus musculus
MedLine Reference 14644997:10175
Journal Blood
Journal Reference v103 i6 p2325
Journal Link http://www.bloodjournal.org/cgi/content/full/103/6/2325
MedLine Reference 10749919:10037
Journal Mol. Biol. Cell
Journal Reference v11 i4 p1129
Journal Link http://www.molbiolcell.org/cgi/content/full/11/4/1129
MedLine Reference 8810340:10115
Journal J. Biol. Chem
Journal Reference v271 i41 p25639
Journal Link http://www.jbc.org/cgi/content/full/271/41/25639
Organism Mus musculus
MedLine Reference 15576456:10348
Journal Mol. Endocrin
Journal Reference v19 i3 p711
Journal Link http://mend.endojournals.org/cgi/content/full/19/3/711
MedLine Reference 9642280:10266
MedLine Reference 9535915:10031
Journal J. Biol. Chem
Journal Reference v273 i15 p9234
Journal Link http://www.jbc.org/cgi/content/full/273/15/9234
MedLine Reference 10499523:10069
Journal Endocrinology
Journal Reference v140 i10 p4659
Journal Link http://endo.endojournals.org/cgi/content/full/140/10/4659
Organism Mus musculus
MedLine Reference 14996702:10118
Journal Blood
Journal Reference v104 i1 p51
Journal Link http://www.bloodjournal.org/cgi/content/full/104/1/51
Organism Mus musculus
MedLine Reference 9774435:10178
Organism Mus musculus
MedLine Reference 10469123:10106
Journal Eur. J. Biochem
Journal Reference v263 i3 p605
Journal Link http://www.ejbiochem.org/cgi/content/full/263/3/605
MedLine Reference 10952974:10459
Journal J. Biol. Chem
Journal Reference v275 i49 p38831
Journal Link http://www.jbc.org/cgi/content/full/275/49/38831
MedLine Reference 9763608:10165
Journal J. Exp. Med
Journal Reference v188 i7 p1287
Journal Link http://www.jem.org/cgi/content/full/188/7/1287
MedLine Reference 9049301:10021
Journal EMBO
Journal Reference v16 i4 p717
Journal Link http://emboj.oupjournals.org/cgi/content/full/16/4/717
Organism Mus musculus
MedLine Reference 8662912:10191
Journal J. Biol. Chem
Journal Reference v271 i24 p14169
Journal Link http://www.jbc.org/cgi/content/full/271/24/14169
Organism Mus musculus
MedLine Reference 10766859:10076
Journal J. Biol. Chem
Journal Reference v275 i16 p12223
Journal Link http://www.jbc.org/cgi/content/full/275/16/12223
Organism Mus musculus
MedLine Reference 10688641:10212
Journal Mol. Cell. Biol
Journal Reference v20 i6 p1931
Journal Link http://mcb.asm.org/cgi/content/full/20/6/1931
Organism Rattus norvegicus
MedLine Reference 12114314:10045
Journal Circulation Res
Journal Reference v91 i1 p4
Journal Link http://circres.ahajournals.org/cgi/content/full/91/1/4
MedLine Reference 7543102:10025
Journal J. Biol. Chem
Journal Reference v270 i31 p18420
Journal Link http://www.jbc.org/cgi/content/full/270/31/18420
Organism Mus musculus
MedLine Reference 14576154:10113
Journal J. Biol. Chem
Journal Reference v279 i5 p3202
Journal Link http://www.jbc.org/cgi/content/full/279/5/3202
Organism Mus musculus
MedLine Reference 8995379:10174
Journal J. Biol. Chem
Journal Reference v272 i2 p894
Journal Link http://www.jbc.org/cgi/content/full/272/2/894
MedLine Reference 10958675:10388
Journal Mol. Cell. Biol
Journal Reference v20 i18 p6779
Journal Link http://mcb.asm.org/cgi/content/full/20/18/6779
Organism Mus musculus
MedLine Reference 11734574:10384
Journal Lipid Res
Journal Reference v42 i12 p2015
Journal Link http://www.jlr.org/cgi/content/full/42/12/2015
MedLine Reference 12417593:10188
Journal J. Biol. Chem
Journal Reference v278 i4 p2199
Journal Link http://www.jbc.org/cgi/content/full/278/4/2199
Organism Mus musculus
MedLine Reference 10066827:10181
Journal J. Biol. Chem
Journal Reference v274 i11 p7583
Journal Link http://www.jbc.org/cgi/content/full/274/11/7583
Organism Rattus norvegicus
MedLine Reference 15192040:10165
Journal Endocrinology
Journal Reference v145 i9 p4213
Journal Link http://endo.endojournals.org/cgi/content/full/145/9/4213
MedLine Reference 8626525:10115
Journal J. Biol. Chem
Journal Reference v271 i14 p8300
Journal Link http://www.jbc.org/cgi/content/full/271/14/8300
MedLine Reference 9013951:5
CellType b cell
Organism Mus musculus
MedLine Reference 7673183:1
Organism Mus musculus
MedLine Reference 10612430:5
Organ liver
Tissue muscle
Organism Mus musculus
MedLine Reference 15964235:0
Organism Mus musculus
CellLineName B104-1-1
MedLine Reference 14734489:6
CellLineName LTED
MedLine Reference 7907978:6
Organism Mus musculus
CellLineName SKBR3
MedLine Reference 8567115:6
MedLine Reference 10762050:1
Organism Mus musculus
MedLine Reference 10924365:3
CellType adipocyte
Organism Rattus norvegicus
MedLine Reference 9230117:2
Organism Rattus norvegicus
MedLine Reference 12941529:4
CellType oocyte
MedLine Reference 12441060:2
Tissue amygdala
Organism Rattus norvegicus
CellLineName LA
MedLine Reference 8950973:7
CellLineName M07E
MedLine Reference 7541035:2
Organism Rattus norvegicus
MedLine Reference 10871841:7
CellLineName MCF7
MedLine Reference 9704577:5
Organ liver
Tissue skeletal muscle
Organism Mus musculus
CellLineName CASE
MedLine Reference 10216087:10021
Journal Blood
Journal Reference v93 i9 p2928
Journal Link http://www.bloodjournal.org/cgi/content/full/93/9/2928
Organism Mus musculus
MedLine Reference 9473212:10274
Journal Blood
Journal Reference v91 i5 p1496
Journal Link http://www.bloodjournal.org/cgi/content/full/91/5/1496
Organism Mus musculus
MedLine Reference 14983012:10144
Journal PNAS
Journal Reference v101 i8 p2345
Journal Link http://www.pnas.org/cgi/content/full/101/8/2345
Organism Mus musculus
MedLine Reference 9490675:10129
Journal Blood
Journal Reference v91 i6 p1924
Journal Link http://www.bloodjournal.org/cgi/content/full/91/6/1924
MedLine Reference 9389692:10091
Journal Blood
Journal Reference v90 i12 p4759
Journal Link http://www.bloodjournal.org/cgi/content/full/90/12/4759
Organism Mus musculus
MedLine Reference 9539773:10163
Journal PNAS
Journal Reference v95 i8 p4538
Journal Link http://www.pnas.org/cgi/content/full/95/8/4538
MedLine Reference 9440699:10161
Journal Circulation Res
Journal Reference v82 i1 p7
Journal Link http://circres.ahajournals.org/cgi/content/full/82/1/7
Organism Mus musculus
MedLine Reference 10986280:10237
Journal J. Biol. Chem
Journal Reference v275 i48 p38040
Journal Link http://www.jbc.org/cgi/content/full/275/48/38040
MedLine Reference 9252406:10240
Journal J. Biol. Chem
Journal Reference v272 i33 p20811
Journal Link http://www.jbc.org/cgi/content/full/272/33/20811
MedLine Reference 9774361:10160
Journal Hypertension
Journal Reference v32 i4 p668
Journal Link http://hyper.ahajournals.org/cgi/content/full/32/4/668
Organism Rattus norvegicus
MedLine Reference 10407026:10207
Organism Mus musculus
MedLine Reference 9950219:10044
Journal Cell Growth and Diff
Journal Reference v10 i1 p61
Journal Link http://cgd.aacrjournals.org/cgi/content/full/10/1/61
MedLine Reference 12101233:10248
Journal Mol. Cell. Biol
Journal Reference v22 i15 p5380
Journal Link http://mcb.asm.org/cgi/content/full/22/15/5380
MedLine Reference 12716736:10262
Journal Diabetes
Journal Reference v52 i5 p1081
Journal Link http://diabetes.diabetesjournals.org/cgi/content/full/52/5/1081
Organism Mus musculus
MedLine Reference 15322256:10023
Journal Mol. Pharm
Journal