Protein : HMG14
Owner Public
URN urn:agi-llid:3150
Hugo ID 4984
Connectivity 89
Name HMG14
Description high mobility group nucleosomal binding domain 1
Notes Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM]
RGD ID 1307761
MGI ID 96120
Cell Localization Nucleus
Pathway p38 Signaling
MAPK signaling
p38 Signaling2
Group Transcription factors
establishment and-or maintenance of chromatin architecture
pyrimidine dimer repair via nucleotide-excision repair
transcription-coupled nucleotide-excision repair
response to UV-B
response to UV-C
nucleus
chromatin
chromatin binding
DNA binding
RNA polymerase II transcription factor activity
positive transcription elongation factor activity
GenBank ID NC_000021
NM_004965
NP_004956
NT_011512
NW_927384
AC_000064
AF064861
AL163279
CAB90453
M21339
AAA52677
AB209245
BAD92482
AK056033
BAB71078
AK130775
AL582106
BC000075
AAH00075
BC023984
AAH23984
BC070153
AAH70153
BC070154
AAH70154
BC071643
AAH71643
BC072672
AAH72672
BC106080
AAI06081
BC107741
AAI07742
BE779939
BT007337
AAP36001
CR597521
CR601793
CR619497
CR619783
CR620500
CR625629
J02621
AAA52676
P05114
Q59G64
Q6NSG7
Q96N32
NC_000082
NM_008251
NP_032277
NT_039625
NW_000109
NW_001030587
AC_000038
AC144797
AC164647
M94283
AK010763
BAC25314
BC083138
AAH83138
BC088834
AAH88834
BU923172
X53476
CAA37569
P18608
Q5HZY9
Q8CEW1
NC_005110
NM_001013184
NP_001013202
NW_001084661
NW_047354
AC_000079
BC086423
AAH86423
Q5U1W8
Source Curated
LocusLink ID 3150
15312
360704
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 163920
Alias HMG14
FLJ27265
FLJ31471
MGC104230
MGC117425
high-mobility group nucleosome binding domain 1
nonhistone chromosomal protein HMG-14
high-mobility group nucleosome binding 1
high-mobility group (nonhistone chromosomal) protein 14
HMG-14
MGC103397
high mobility group nucleosomal binding domain 1
high mobility group protein 14
GO ID 0003677
0003702
0008159
0000785
0005634
0003682
0006325
0000720
0010224
0010225
0006283
Swiss-Prot Accession P05114
Q59G64
Q6NSG7
Q96N32
P18608
Q5HZY9
Q8CEW1
Q5U1W8
Unigene ID Hs.356285
Mm.2756
Rn.4120