Protein : HSPB1


Owner	Public
URN	urn:agi-llid:3315
Hugo ID	5246
Connectivity	812
Name	HSPB1
Description	heat shock 27kDa protein 1
Notes	putative heat shock protein; human homolog may suppress polyglutamine-mediated cell death and mutations in human gene are associated with various neuropathies and some forms of Charcot-Marie-Tooth disease [RGD]


RGD ID	61306


MGI ID	96240


Cell Localization	Nucleus


Pathway	p38 MAPK
	p38 Signaling
	Inhibition of Apoptosis
	MAPK signaling
	p38 Signaling2


Group	cell motility
	anti-apoptosis
	regulation of translational initiation
	protein folding
	response to unfolded protein
	cell surface
	insoluble fraction
	soluble fraction
	cytoplasm
	proteasome complex (sensu Eukaryota)
	contractile fiber
	Z disc
	nucleus
	cytoskeleton
	plasma membrane
	protein binding
	ubiquitin binding


GenBank ID	NC_000007
	NM_001540
	NP_001531
	NT_007933
	NT_079595
	NW_923484
	AC_000050
	AC_000068
	AC006388
	DQ379985
	ABC88475
	L39370
	AAA62175
	AB020027
	BAB17232
	AL050380
	BC000510
	AAH00510
	BC012292
	AAH12292
	BC012768
	AAH12768
	BC014920
	AAH14920
	BC073768
	AAH73768
	BT019888
	AAV38691
	CR407614
	CAG28542
	CR536489
	CAG38728
	CR591310
	CR603713
	CR605148
	CR606208
	CR607252
	CR608836
	S74571
	AAB20722
	U90906
	AAB51056
	X16477
	CAA34498
	X54079
	CAA38016
	P04792
	Q6FI47
	Q96C20
	Q96EI7
	Q9UC35
	NC_000071
	NM_013560
	NP_038588
	NT_039314
	NW_000238
	NW_001030796
	AC_000027
	AC084162
	L07577
	AAA37861
	L11608
	AAA37862
	L11609
	AF047377
	AAD02432
	AK003119
	BAB22579
	AK010663
	BAB27099
	AK019498
	BAB31762
	AK168927
	BAE40740
	BC018257
	AAH18257
	BC090388
	BC099463
	AAH99463
	BG070071
	U03560
	AAA18335
	U03561
	AAA18336
	U03562
	AAA18337
	X14686
	CAB37341
	X14687
	CAA32818
	P14602
	Q545F4
	Q9Z2L3
	NC_005111
	NM_031970
	NP_114176
	NW_001084677
	NW_047370
	AC_000080
	S67755
	AAB29536
	M86389
	AAA41353
	P42930


Source	Curated


LocusLink ID	3315
	15507
	24471


Organism	Homo sapiens
	Mus musculus
	Rattus norvegicus


OMIM ID	602195
	606595
	608634


Alias	CMT2F
	HSP27
	HSP28
	Hsp25
	HS.76067
	DKFZp586P1322
	heat shock 27kDa protein 1
	heat shock 27kD protein 1
	27kDa
	heat shock protein 1
	heat shock protein, 25 kDa
	Heat shock 27 kDa protein
	heat shock 27 kDa protein 1


GO ID	0005515
	0006916
	0006928
	0006457
	0006446
	0006986
	0009986
	0005737
	0005856
	0030018
	0043292
	0005626
	0005634
	0005886
	0005625
	0043130
	0000502


Swiss-Prot Accession	P04792
	Q6FI47
	Q96C20
	Q96EI7
	Q9UC35
	P14602
	Q545F4
	Q9Z2L3
	P42930


Unigene ID	Hs.520973
	Mm.13849
	Rn.3841