Protein : TNFRSF6


Owner	Public
URN	urn:agi-llid:355
Hugo ID	11920
Connectivity	2413
Name	TNFRSF6
Description	Tumor necrosis factor receptor superfamily, member 6
Notes	Tnfsf6/Fasl receptor [RGD]


RGD ID	619831


MGI ID	95484


Cell Localization	Plasma membrane


Pathway	FAS signaling
	FasL
	Mitochondrial control of Apoptosis
	Death receptor signaling
	p38 Signaling
	Apoptosis
	TNFRSF6 -> DDIT3 signaling pathway
	TNFRSF6 -> FOXO3A signaling pathway
	TNFRSF6 -> HSF1 signaling pathway
	TNFRSF6 -> RB1-E2F1 signaling pathway
	TNFRs -> AP-1 signaling pathway
	TNFRs -> ATF2 signaling pathway
	TNFRs -> CREB1 signaling pathway
	TNFRs -> ELK1-SRF signaling pathway
	TNFRs -> ELK4-SRF signaling pathway
	TNFRs -> NF-kB signaling pathway
	TNFRs -> TP53 signaling pathway
	Copy of 'Apoptosis'
	Apoptosis2
	p38 Signaling2


Group	Receptors
	signal transduction
	negative thymic T cell selection
	apoptosis
	activated T cell apoptosis
	inflammatory cell apoptosis
	regulation of apoptosis
	transformed cell apoptosis
	anti-apoptosis
	induction of apoptosis
	induction of apoptosis via death domain receptors
	protein complex assembly
	immune response
	membrane
	soluble fraction
	external side of plasma membrane
	cytosol
	integral to membrane
	caveola
	protein binding
	identical protein binding
	tumor necrosis factor receptor activity
	receptor activity
	transmembrane receptor activity


Source	Curated


OMIM ID	134637
	601859


Alias	APT1
	CD95
	FAS1
	APO-1
	FASTM
	ALPS1A
	TNFRSF6
	tumor necrosis factor receptor superfamily, member 6
	Fas antigen
	CD95 antigen
	OTTHUMP00000059646
	apoptosis antigen 1
	APO-1 cell surface antigen
	lpr
	TNFR6
	AI196731
	Fas (TNF receptor superfamily member)
	lymphoproliferation
	Fas receptor
	apo-1 antigen
	Fas antigen (ATP1)
	apoptosis-mediating surface antigen FAS