Regulation :

Effect unknown
Owner Public
URN urn:agi-Regulation:inout-urn:agi-complex:3000097:out-urn:agi-llid:7128::unknown
Entities Nuclear factor NF kappa B ---> TNFAIP3
References 2
Connectivity 2

MedLine Reference 12586352:2
Sentence Among others, the NF-kappa B-dependent zinc finger protein A20 is involved in the negative feedback regulation of NF-kappa B activation in response to tumor necrosis factor (TNF).
Source Curated

MedLine Reference 12167698:4
Sentence We show here that the zinc finger protein A20 is an NF-kappaB-inducible gene that can protect the IKKgamma-deficient cells from TNF-induced apoptosis by disrupting the recruitment of the death domain signaling molecules TRADD and RIP to the receptor signaling complex.
Source Curated
CellType t cell
CellLineName JURKAT