Binding :


Connectivity	2
Owner	Public
URN	urn:agi-Binding:inout-urn:agi-llid:7189:inout-urn:agi-llid:3656:
Entities	IRAK2 ---- TRAF6
References	20


MedLine Reference	12659850:6
Sentence	Finally, IRAK2 interactions with TRAF6 were mapped and demonstrate differences from more proximal signaling intermediates.


MedLine Reference	10190904:10280
Sentence	IRAK2 also interacts with MyD88 and TRAF6 ( 19 ).
Journal	J. Exp. Med
Journal Reference	v189 i7 p1129
Journal Link	http://www.jem.org/cgi/content/full/189/7/1129
Organism	Mus musculus


MedLine Reference	9374458:1058
Sentence	We therefore determined whether IRAK-2 interacted with TRAF6.
Journal	Science
Journal Reference	v278 i5343 p1612 (1997)
Journal Link	http://www.sciencemag.org/cgi/content/full/278/5343/1612


Journal	Science
Journal Reference	v278 i5343 p1612 (1997)
Journal Link	http://www.sciencemag.org/cgi/content/full/278/5343/1612
CellLineName	293T


MedLine Reference	10882729:10040
Journal	J. Biol. Chem
Journal Reference	v275 i39 p29946
Journal Link	http://www.jbc.org/cgi/content/full/275/39/29946


MedLine Reference	11744690:10187
Journal	J. Biol. Chem
Journal Reference	v277 i10 p7808
Journal Link	http://www.jbc.org/cgi/content/full/277/10/7808
Organism	Mus musculus


MedLine Reference	15998638:10112
Journal	J. Biol. Chem
Journal Reference	v280 i35 p30838
Journal Link	http://www.jbc.org/cgi/content/full/280/35/30838
Organism	Mus musculus


MedLine Reference	12368275:10049
Journal	J. Biol. Chem
Journal Reference	v277 i51 p49205
Journal Link	http://www.jbc.org/cgi/content/full/277/51/49205
Organism	Mus musculus


MedLine Reference	12566418:10202
Journal	J. Exp. Med
Journal Reference	v197 i3 p343
Journal Link	http://www.jem.org/cgi/content/full/197/3/343
Organism	Mus musculus


MedLine Reference	10383454
Sentence	IRAK-2 interacts with TRAF6
Source	Curated


MedLine Reference	10383454:1137
Sentence	IRAK-2 has also been shown to interact with MyD88 and TRAF6 upon overexpression ( 19 ).
Journal	J. Biol. Chem
Journal Reference	v274 i27 p19403 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/27/19403
Organism	drosophila
Source	Curated


MedLine Reference	12368275:1049
Sentence	IRAK and IRAK2 have been shown to interact with tumor necrosis factor receptor-associated factor-6 (TRAF-6) ( 24 ).
Journal	J. Biol. Chem
Journal Reference	v277 i51 p49205 (2002)
Journal Link	http://www.jbc.org/cgi/content/full/277/51/49205
Organism	mouse
Source	Curated


MedLine Reference	10075662:1032
Sentence	Furthermore, TRAF6 interacts with interleukin-1 receptor-associated kinase 1 and 2 (IRAK1 and IRAK2) ( 17-19 ).
CellType	osteoclast
Journal	J. Biol. Chem
Journal Reference	v274 i12 p7724 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/12/7724
Source	Curated


MedLine Reference	11744690:1189
Sentence	Taken together our data suggest that active Ras can associate with a multiprotein complex containing IRAK , IRAK-2, Traf-6, and TAK-1.
Journal	J. Biol. Chem
Journal Reference	v277 i10 p7808 (2002)
Journal Link	http://www.jbc.org/cgi/content/full/277/10/7808
Organism	mouse
Source	Curated


MedLine Reference	10882729:1040
Sentence	Following their association with the IL-1R complex, IRAK and IRAK-2 have been shown to interact with tumor necrosis factor receptor-associated factor-6 (TRAF-6) ( 19 , 24 ).
Journal	J. Biol. Chem
Journal Reference	v275 i39 p29946 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/39/29946
Source	Curated


MedLine Reference	9374458
Source	Curated


MedLine Reference	10373512:1026
Journal	Mol. Cell. Biol
Journal Reference	v19 i7 p4643 (1999)
Journal Link	http://mcb.asm.org/cgi/content/full/19/7/4643
Organism	mouse
Source	Curated


Journal	J. Exp. Med
Journal Reference	v197 i3 p343 (2003)
Journal Link	http://www.jem.org/cgi/content/full/197/3/343
Source	Curated


Journal	J. Exp. Med
Journal Reference	v197 i3 p343 (2003)
Journal Link	http://www.jem.org/cgi/content/full/197/3/343
Source	Curated


MedLine Reference	10190904:1279
Journal	J. Exp. Med
Journal Reference	v189 i7 p1129 (1999)
Journal Link	http://www.jem.org/cgi/content/full/189/7/1129
Organism	mouse
Source	Curated