Protein : PLCG2


Owner	Public
URN	urn:agi-llid:5336
Hugo ID	9066
Connectivity	281
Name	PLCG2
Description	phospholipase C, gamma 2
Notes	has phosphoinositide-specific phospholipase C activity [RGD]


RGD ID	3348


MGI ID	97616


Pathway	HGF
	EPHB2
	EGF signaling
	PDGFRB
	PDGF signaling
	MAPK-ERK in Growth and Differentiation
	PDGFRA
	EPHA4
	NGF signaling
	EGF
	B-cell receptor -> AP-1 signaling pathway
	B-cell receptor -> NF-kB signaling pathway
	B-cell receptor -> NFAT5 signaling pathway
	B-cell receptor -> NFATC1 signaling pathway
	B-cell receptor -> NFATC2 signaling pathway
	B-cell receptor -> NFATC3 signaling pathway
	B-cell receptor -> NFATC4 signaling pathway
	CD19 -> AP-1 signaling pathway
	CD19 -> ELK1-SRF signaling pathway
	CD19 -> ELK4-SRF signaling pathway
	CD22/72 -> AP-1 signaling pathway
	CD22/72 -> NF-kB signaling pathway
	CD22/72 -> NFAT5 signaling pathway
	CD22/72 -> NFATC1 signaling pathway
	CD22/72 -> NFATC2 signaling pathway
	CD22/72 -> NFATC3 signaling pathway
	CD22/72 -> NFATC4 signaling pathway


Group	Ph
	Sh2
	signal transduction
	cell surface receptor linked signal transduction
	intracellular signaling cascade
	phospholipid metabolism
	lipid catabolism
	signal transducer activity
	protein binding
	calcium ion binding
	hydrolase activity
	phospholipase C activity
	phosphoinositide phospholipase C activity


Source	Curated


OMIM ID	600220


Alias	phospholipase C, gamma 2 (phosphatidylinositol-specific)
	phospholipase C gamma 2
	Phospholipase C, gamma 2 (phosphatidylyinositol-specific)
	Plcg-2
	MGC38590
	phospholipase C, gamma 2