Protein : Grb2
Owner Public
URN urn:agi-llid:2885
Hugo ID 4566
Connectivity 763
Name Grb2
Description growth factor receptor bound protein 2
Notes acts as a link between tyrosine kinase receptors and Ras signaling [RGD]
RGD ID 619758
MGI ID 95805
Pathway LT-alpha
p40 MAPK
HGF
Insulin Receptor Signaling
RANKL
Neurotensin
Antiapoptotic Pathways From IGF-1R
Jak-Stat Pathway from IL6 Receptor
Insulin pathway
EGF signaling
EPHB1
PDGFRB
p38 Signaling
PDGF signaling
opioids OPRD1
TNF-alpha
MAPK-ERK in Growth and Differentiation
PDGFRA
Erythropoietin signaling
IL-6 signaling
G-protein Coupled Receptor signaling
Bombesin
Oxytocin
PTEN signaling
SAPK-JNK Signaling
IL-3 signaling
CREB signaling
EPHA2
Vasopressin
IL-2 signaling
Cholecystokinin
Gastrin
Substance P
NGF signaling
Endothelin
IL-1 and IL-6 signaling
EGF
Integrin Signaling
Nociceptin
AGTR1 -> ELK1-SRF signaling pathway
PTPRC -> BCL6 signaling pathway
AGTR1 -> ELK4-SRF signaling pathway
EDG2 -> ELK4-SRF signaling pathway
AGTR1 -> TP53 signaling pathway
AGTR2 -> CREB1 signaling pathway
EGFR -> AP-1 signaling pathway
AGTR2 -> ELK1-SRF signaling pathway
AGTR2 -> ELK4-SRF signaling pathway
NTRK1 -> SMAD3 signaling pathway
NTRKs -> AP-1 signaling pathway
NTRKs -> CREB1 signaling pathway
NTRKs -> ELK1-SRF signaling pathway
NTRKs -> ELK4-SRF signaling pathway
AGTR2 -> TP53 signaling pathway
ERBB2 -> ETV4 signaling pathway
EGFR -> ATF2 signaling pathway
EGFR -> SMAD1 signaling pathway
NTRKs -> MYC signaling pathway
NTRKs -> STAT5A signaling pathway
NTRKs -> TP53 signaling pathway
IGF1R -> ELK1-SRF signaling pathway
EGFR/ERBB2 -> HIF1A signaling pathway
ERBB2/3 -> SP1 signaling pathway
IGF1R -> ELK4-SRF signaling pathway
IGF1R -> HIF1A signaling pathway
IGF1R -> MYC signaling pathway
IGF1R -> SREBF1 signaling pathway
EGFR/ERBB2 -> TP53 signaling pathway
F2R -> AP-1 signaling pathway
PECAM1 -> SP1 signaling pathway
PLAUR -> ELK1-SRF signaling pathway
RET -> HSF1 signaling pathway
PLAUR -> ELK4-SRF signaling pathway
F2R -> CREB1 signaling pathway
F2R -> ELK1-SRF signaling pathway
F2R -> ELK4-SRF signaling pathway
F2R -> SP1 signaling pathway
EPOR -> ELK1-SRF signaling pathway
EPOR -> ELK4-SRF signaling pathway
SELE -> ELK1-SRF signaling pathway
EPOR -> FOS signaling pathway
FCGR3A -> ELK1-SRF signaling pathway
SELE -> ELK4-SRF signaling pathway
FCGR3A -> ELK4-SRF signaling pathway
ERBB2 -> EP300 signaling pathway
ERBB2 -> ETS1 signaling pathway
ERBB2 -> ETS2 signaling pathway
ERBB2 -> ETV1 signaling pathway
IL2R -> ELK1-SRF signaling pathway
IL2R -> ELK4-SRF signaling pathway
IL2R -> MYC signaling pathway
T-cell receptor -> AP-1 signaling pathway
IL4R -> ELK1-SRF signaling pathway
IL4R -> ELK4-SRF signaling pathway
IL4R -> HMGY signaling pathway
IL6R -> CEBPB signaling pathway
FGFRs -> RUNX2 signaling pathway
IL6R -> ELK1-SRF signaling pathway
IL6R -> ELK4-SRF signaling pathway
INSR -> ELK1-SRF signaling pathway
INSR -> ELK4-SRF signaling pathway
INSR -> SREBF1 signaling pathway
INSR -> SREBF2 signaling pathway
ITGB1 -> AP-1 signaling pathway
ITGB1 -> ELK1-SRF signaling pathway
ITGB1 -> ELK4-SRF signaling pathway
ITGB1 -> SREBF1 signaling pathway
ITGB1 -> SREBF2 signaling pathway
KDR -> ATF1 signaling pathway
GFRs -> AP-1 signaling pathway
GFRs -> CREB1 signaling pathway
GFRs -> CREBBP signaling pathway
GFRs -> ELK1-SRF signaling pathway
ADRA1B -> ELK1-SRF signaling pathway
KDR -> ATF2 signaling pathway
GFRs -> ELK4-SRF signaling pathway
KDR -> CREB1 signaling pathway
CHRM1 -> CREB1 signaling pathway
GFRs -> MYC signaling pathway
GFRs -> NCOR2 signaling pathway
KDR -> ELK1-SRF signaling pathway
KDR -> ELK4-SRF signaling pathway
KDR -> NFATC1 signaling pathway
KIT -> MITF signaling pathway
GHR -> ELK1-SRF signaling pathway
CHRM1 -> ELK1-SRF signaling pathway
CHRM1 -> ELK4-SRF signaling pathway
CHRNA7 -> CREB1 signaling pathway
ADRA1B -> ELK4-SRF signaling pathway
GHR -> ELK4-SRF signaling pathway
GHR -> MYC signaling pathway
LEPR -> ELK1-SRF signaling pathway
ADRA1B -> STAT3 signaling pathway
LEPR -> ELK4-SRF signaling pathway
GRM1/5 -> CREB1 signaling pathway
MPL -> CREB1 signaling pathway
MPL -> SP1 signaling pathway
MPL -> SPI1 signaling pathway
NCAM1 -> CREB1 signaling pathway
NCAM1 -> ELK1-SRF signaling pathway
NCAM1 -> ELK4-SRF signaling pathway
NCAM1 -> MYC signaling pathway
TNFRSF1A -> AP-1 signaling pathway
TNFRSF1A -> ATF2 signaling pathway
DRD2 -> AP-1 signaling pathway
TNFRSF1A -> CREB1 signaling pathway
TNFRSF1A -> ELK1-SRF signaling pathway
TNFRSF1A -> ELK4-SRF signaling pathway
DRD2 -> CREB1 signaling pathway
DRD2 -> ELK1-SRF signaling pathway
AGTR1 -> CREB1 signaling pathway
TNFRSF1A -> TP53 signaling pathway
DRD2 -> ELK4-SRF signaling pathway
EDG2 -> ELK1-SRF signaling pathway
p38 Signaling2
tshirt 'Insulin Receptor Signaling' 1
Group Sh2
cell-cell signaling
intracellular signaling cascade
epidermal growth factor receptor signaling pathway
insulin receptor signaling pathway
MAPKKK cascade
Ras protein signal transduction
membrane
cytoplasm
cytosol
vesicle membrane
protein binding
insulin receptor substrate binding
SH3-SH2 adaptor activity
epidermal growth factor receptor binding
receptor activity
GenBank ID NC_000017
NM_002086
NP_002077
NM_203506
NP_987102
NT_010641
NW_926918
AC_000060
AC011933
AF063618
AAC72075
AA452034
AF171699
AAQ13606
AF246238
AAG44485
AF302079
AAG27442
AF498925
AAM21073
AK024539
BAB14923
AK091010
BC000631
AAH00631
BC009417
BC019082
BC033644
BC039827
BC043007
BI459414
BQ073225
BQ962129
CR450363
CAG29359
CR541942
CAG46740
L29511
AAC37549
M96995
AAA58448
X62852
CAA44664
P62993
Q6ICN0
Q7Z4F5
Q9H2Q4
Q9H7G8
Q9HAU2
NC_000077
NM_008163
NP_032189
NT_165773
NW_000040
NW_001030434
AC_000033
AL645852
AL732491
AI323718
AK077750
AK079087
AK148148
BAE28376
AK153557
BAE32093
AK155800
BAE33439
AK166142
BAE38595
AK170845
BAE42068
AK172002
AK177056
AK180406
AK181485
AK192421
AK196759
AK211391
BC052377
AAH52377
BC085254
AAH85254
BG064712
BG078047
D85748
BAA12862
U07617
AAB40022
Q60631
NC_005109
NM_030846
NP_110473
NW_001084656
NW_047343
AC_000078
AA926364
BC091144
AAH91144
D49846
BAA08645
D49847
BAA08646
D49848
BAA08647
X62853
CAA44665
P62994
Q5BKA7
Q63058
Source Curated
LocusLink ID 2885
14784
81504
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 108355
Alias ASH
Grb3-3
MST084
MSTP084
EGFRBP-GRB2
growth factor receptor-bound protein 2
HT027
abundant SRC homology
growth factor receptor-bound protein 3
epidermal growth factor receptor-binding protein GRB2
AA408164
growth factor receptor bound protein 2
MGC108668
GO ID 0005070
0005154
0043560
0007265
0007267
0007173
0008286
0007242
0005829
0005515
0004872
0000165
0005737
0016020
0012506
Swiss-Prot Accession P62993
Q6ICN0
Q7Z4F5
Q9H2Q4
Q9H7G8
Q9HAU2
Q60631
P62994
Q5BKA7
Q63058
Unigene ID Hs.444356
Hs.633064
Mm.383426
Rn.3360
Rn.163461