Regulation :


Effect	positive
Owner	Public
URN	urn:agi-Regulation:inout-urn:agi-protfc:Rac%20GTPase:out-urn:agi-llid:5063::positive
Entities	Rac GTPase --+> PAK3
References	2
Connectivity	2


MedLine Reference	12244132:1
Sentence	Group 1 PAKs (PAK1-3) are involved in cell migration, and are activated by pro-migratory stimuli and by Cdc42/Rac GTPases.


MedLine Reference	11356824:1020
Sentence	RESULTS DISCUSSION REFERENCES Several distinct Ser/Thr kinases of the PAK 1 family such as PAK1, PAK2, and PAK3 are activated by CDC42/Rac GTPases and the SH3 proteins called PIX/Cool ( 1 ).
Tissue	egg
Journal	J. Biol. Chem
Journal Reference	v276 i29 p26741 (2001)
Journal Link	http://www.jbc.org/cgi/content/full/276/29/26741
Organism	mouse
Source	Curated
CellType	fibroblast