Protein : Rock1

Owner Public
URN urn:agi-llid:6093
Hugo ID 10251
Connectivity 153
Name Rock1
Description Rho-associated coiled-coil forming kinase 1
Notes protein serine/threonine kinase; involved in intracellular signaling [RGD]

RGD ID 620424

MGI ID 107927

Pathway Death receptor signaling
PKC in Myosine regulation
Erk-PI3K in Collagen Binding
Integrin Signaling

Group Kinases
Ph
signal transduction
intracellular signaling cascade
Rho protein signal transduction
apoptosis
negative regulation of neuron apoptosis
microtubule-based movement
cytoskeleton organization and biogenesis
actin cytoskeleton organization and biogenesis
protein amino acid phosphorylation
intracellular
cytoskeleton
microtubule
structural molecule activity
nucleotide binding
metal ion binding
zinc ion binding
diacylglycerol binding
ATP binding
GTP-Rho binding
transferase activity
kinase activity
protein kinase activity
protein serine-threonine kinase activity
protein-tyrosine kinase activity

GenBank ID NC_000018
NM_005406
NP_005397
NT_010966
NW_927095
AC_000061
AC022795
AC036178
AB208965
BAD92202
AK057038
AU121527
BC041849
AAH41849
BC113114
AAI13115
U43195
AAB02814
Q13464
Q59GZ4
NC_000084
NM_009071
NP_033097
NT_039674
NW_000134
NW_001030629
AC_000040
AC102437
AC132622
AI528704
AK004265
AK050269
BAC34154
AK077297
AK085974
BAC39581
AK149793
BAE29089
AK171291
BAE42373
AV289751
BB667679
BC057154
AAH57154
BC066873
BG068786
BG074301
BG081800
BG088815
BI662863
BM240191
U58512
AAC53132
P70335
NC_005117
NM_031098
NP_112360
NW_001084733
NW_047506
AC_000086
AY325220
AAP92621
U61266
AAB37571
Q63644

Source Curated

LocusLink ID 6093
19877
81762

Organism Homo sapiens
Mus musculus
Rattus norvegicus

OMIM ID 601702

Alias MGC43611
P160ROCK
MGC131603
Rho-associated, coiled-coil containing protein kinase 1
p160-ROCK
Rock-I
1110055K06Rik
Rho-associated coiled-coil forming kinase 1
Rho-associated kinase beta

GO ID 0005524
0019992
0046872
0000166
0004674
0016740
0008270
0007266
0030036
0006915
0007242
0006468
0005856
0005622
0016301
0004672
0004713
0005198
0007018
0043524
0007165
0005874
0017049
0007010

Swiss-Prot Accession Q13464
Q59GZ4
P70335
Q63644

Unigene ID Hs.306307
Mm.6710
Rn.89756