Protein : ITGB1


Owner	Public
URN	urn:agi-llid:3688
Hugo ID	6153
Connectivity	760
Name	ITGB1
Description	integrin beta 1 (fibronectin receptor beta)
Notes	beta subunit of integrin receptor which binds collagen [RGD]


RGD ID	2927


MGI ID	96610


Cell Localization	Plasma membrane


Pathway	integrin alpha2beta1
	integrin alpha1beta1
	integrin alpha11beta1
	integrin alpha9beta1
	integrin alpha10beta1
	integrin alpha8beta1
	integrin alpha7beta1
	integrin alpha6beta1
	PTEN signaling
	integrin alphaVbeta1
	integrin alpha5beta1
	Erk-PI3K in Collagen Binding
	integrin alpha4beta1
	integrin alpha3beta1
	Integrin Signaling
	ITGB1 -> AP-1 signaling pathway
	ITGB1 -> CTNNB1 signaling pathway
	ITGB1 -> ELK1-SRF signaling pathway
	ITGB1 -> ELK4-SRF signaling pathway
	ITGB1 -> ICAP-1A signaling pathway
	ITGB1 -> NF-kB signaling pathway
	ITGB1 -> SREBF1 signaling pathway
	ITGB1 -> SREBF2 signaling pathway


Group	Receptors
	development
	cell adhesion
	homophilic cell adhesion
	cell-matrix adhesion
	integrin-mediated signaling pathway
	negative regulation of cell differentiation
	G1-S transition of mitotic cell cycle
	regulation of progression through cell cycle
	cell migration
	positive regulation of cell proliferation
	cellular defense response
	membrane
	synaptosome
	ruffle
	cytoplasm
	plasma membrane
	integral to membrane
	integrin complex
	extracellular space
	protein binding
	cell adhesion molecule binding
	identical protein binding
	integrin binding
	protein heterodimerization activity
	receptor activity


Source	Curated


OMIM ID	135630


Alias	CD29
	FNRB
	MDF2
	VLAB
	GPIIA
	MSK12
	integrin beta 1
	OTTHUMP00000046253
	OTTHUMP00000063731
	OTTHUMP00000063732
	OTTHUMP00000063733
	integrin VLA-4 beta subunit
	fibronectin receptor beta subunit
	AA409975
	AA960159
	4633401G24Rik
	integrin beta 1 (fibronectin receptor beta)
	beta1 integrin