ProtModification :

Mechanism phosphorylation
Owner Public
URN urn:agi-ProtModification:inout-urn:agi-llid:2932:out-urn:agi-llid:47::unknown
Entities GSK3B ---> ACLY
References 3
Connectivity 2
Effect unknown
MedLine Reference 1332698:5
Sentence Conversely, both alpha- and beta-forms of GSK-3 phosphorylated ATP-citrate lyase at the same site(s) targeted by ACLK.
Organism bovine
Organ brain
Source Curated
MedLine Reference 7669753:6
Sentence CL phosphorylated by cAMP-dependent protein kinase or by this kinase and glycogen synthase kinase-3 (GSK-3) decreases the apparent Vmax without changing the apparent Km.
Organism mouse
Source Curated
MedLine Reference 10688912:1205
Sentence In addition to its effects on glycogen synthase, GSK3 is involved in a great variety of cellular responses, including phosphorylation of ATP-citrate lyase and the transcription factors C/EBPalpha and heat shock transcription factor 1 ( 31-33 , 52 ).
Journal PNAS
Journal Reference v97 i5 p2355 (2000)
Journal Link http://www.pnas.org/cgi/content/full/97/5/2355
Organ liver
Source Curated