Binding :

Connectivity 2
Owner Public
URN urn:agi-Binding:inout-urn:agi-llid:2932:inout-urn:agi-go:0004691:
Entities GSK3B ---- PKA
References 3
MedLine Reference 11035810:10131
Sentence To explore the possibility that PKA may function as a GSK-3 kinase that directly phosphorylates GSK-3, we examined whether PKA physically interacts with GSK-3 in intact cells.
Journal PNAS
Journal Reference v97 i22 p11960
Journal Link http://www.pnas.org/cgi/content/full/97/22/11960
MedLine Reference 12147701:1055
Sentence Here we show that GSK-3eta, PKA , PP1 , and AKAP220 form a complex.
Journal J. Biol. Chem
Journal Reference v277 i40 p36955 (2002)
Journal Link http://www.jbc.org/cgi/content/full/277/40/36955
Organism yeast
Source Curated
MedLine Reference 11035810:1142
Sentence Because GSK-3 also coimmunoprecipitated with the PKA regulatory subunit RII and the association was not affected by forskolin (Fig. 3 C ), it seems that the association of PKAc with GSK-3 is indirect, mediated by PKA regulatory subunits or A-kinase-anchoring proteins.
Journal PNAS
Journal Reference v97 i22 p11960 (2000)
Journal Link http://www.pnas.org/cgi/content/full/97/22/11960
Source Curated
CellLineName HEK 293