Protein : AKT1
Owner Public
URN urn:agi-llid:207
Hugo ID 391
Connectivity 4088
Name AKT1
Description thymoma viral proto-oncogene 1
Notes inhibits JUN kinase activation and mediates inhibition of apoptosis [RGD]
RGD ID 2081
MGI ID 87986
Pathway p40 MAPK
Insulin Receptor Signaling
Antiapoptotic Pathways From IGF-1R
Jak-Stat Pathway from IL6 Receptor
Mitochondrial control of Apoptosis
ACH-R in apoptosis
AKT signaling
Inhibition of Apoptosis
PTEN signaling
CREB signaling
Apoptosis
NOTCH1 -> NF-kB signaling pathway
NTRK1 -> MYCN signaling pathway
NTRKs -> FOXO1A signaling pathway
IGF1R -> CEBPA signaling pathway
NTRKs -> FOXO3A signaling pathway
EGFR/ERBB2 -> HIF1A signaling pathway
IGF1R -> FOXO1A signaling pathway
IL12R -> NF-kB signaling pathway
IL12R -> NFATC1 signaling pathway
RET -> HSF1 signaling pathway
IL15R -> NF-kB signaling pathway
F2R -> NF-kB signaling pathway
IL15R -> NFATC2 signaling pathway
PTAFR -> NF-kB signaling pathway
EPOR -> NF-kB signaling pathway
CD19 -> NF-kB signaling pathway
IL7R -> FOXO1A signaling pathway
IL7R -> FOXO3A signaling pathway
IL7R -> NF-kB signaling pathway
TEK -> FOXO1A signaling pathway
INSR -> CTNNB1 signaling pathway
INSR -> FOXA2 signaling pathway
INSR -> FOXO1A signaling pathway
INSR -> FOXO3A signaling pathway
INSR -> FOXO6 signaling pathway
CD28 -> NF-kB signaling pathway
INSR -> SREBF1 signaling pathway
CD28 -> NFAT5 signaling pathway
ITGAM/ITGB2 -> CEBPB signaling pathway
CD28 -> NFATC1 signaling pathway
CD28 -> NFATC2 signaling pathway
CD28 -> NFATC3 signaling pathway
CD28 -> NFATC4 signaling pathway
FSHR -> FOXO1A signaling pathway
ITGAM/ITGB2 -> NF-kB signaling pathway
TLR1/2 -> NF-kB signaling pathway
ADORA1 -> NF-kB signaling pathway
ITGB1 -> CTNNB1 signaling pathway
ITGB1 -> NF-kB signaling pathway
KDR -> CTNNB1 signaling pathway
GFRs -> FOXO3A signaling pathway
TLR2/6 -> NF-kB signaling pathway
GHR -> NF-kB signaling pathway
ADRB1 -> STAT3 signaling pathway
ADRB2 -> STAT3 signaling pathway
MPL -> SPI1 signaling pathway
DDR1 -> NF-kB signaling pathway
ADRB3 -> STAT3 signaling pathway
ICAM2 -> CTNNB1 signaling pathway
AGER -> NF-kB signaling pathway
ICAM2 -> FOXO1A signaling pathway
ICAM2 -> FOXO3A signaling pathway
ICAM2 -> MLLT7 signaling pathway
DRD2 -> NF-kB signaling pathway
ICAM2 -> STAT3 signaling pathway
TNFRSF5/13B -> NFATC1 signaling pathway
Copy of 'Apoptosis'
Apoptosis2
AKT signaling2
Apoptosis2
ACH-R in apoptosis'-2
tshirt 'Insulin Receptor Signaling' 2
tshirt 'Insulin Receptor Signaling' 3
Group Kinases
Ph
signal transduction
G-protein coupled receptor protein signaling pathway
insulin receptor signaling pathway
insulin-like growth factor receptor signaling pathway
germ cell development
transport
apoptosis
apoptotic mitochondrial changes
negative regulation of apoptosis
anti-apoptosis
regulation of survival gene product activity
positive regulation of cell growth
glucose metabolism
protein biosynthesis
glycogen biosynthesis
regulation of protein biosynthesis
regulation of translation
glycogen metabolism
protein amino acid phosphorylation
protein ubiquitination
anagen
nitric oxide biosynthesis
protein catabolism
carbohydrate metabolism
inflammatory response
response to heat
lamellipodium
cytoplasm
nucleus
spindle
nucleotide binding
protein binding
ATP binding
identical protein binding
transferase activity
kinase activity
protein kinase activity
protein serine-threonine kinase activity
protein-tyrosine kinase activity
receptor signaling protein serine-threonine kinase activity
sugar porter activity
GenBank ID NC_000014
NM_001014431
NP_001014431
NM_001014432
NP_001014432
NM_005163
NP_005154
NT_026437
NW_925561
AC_000057
A62733
CAA03677
A63232
CAA03712
AF283830
AAL55732
AL583722
AL590327
AK094287
AK122894
AK127193
AK131465
BAD18610
BC000479
AAH00479
BC001737
AAH01737
BC063408
BC084538
AAH84538
BX647722
BX648205
CN414251
CR611982
M63167
AAA36539
X61037
CAA43372
P31749
Q6ZMW5
Q9BV07
NC_000078
NM_009652
NP_033782
NT_039551
NW_000055
NW_001030504
AC_000034
AC124373
AF534134
AAN04036
AK040758
BAC30695
AK154936
BAE32937
AK196375
AK211494
AK214116
AK216454
BC066018
AAH66018
BE952690
BG064484
BG077899
M94335
AAA18254
X65687
CAA46620
P31750
NC_005105
NM_033230
NP_150233
NW_001084847
NW_047762
AC_000074
D30040
BAA06279
P47196
Source Curated
LocusLink ID 207
11651
24185
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 164730
181500
Alias PKB
RAC
PRKBA
MGC99656
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1
protein kinase B
rac protein kinase alpha
RAC-alpha serine/threonine-protein kinase
murine thymoma viral (v-akt) oncogene homolog-1
Akt
PKB/Akt
PKBalpha
thymoma viral proto-oncogene 1
RAC protein kinase alpha RAC-PK alpha
murine thymoma viral (v-akt) oncogene homolog 1
GO ID 0005524
0042802
0000166
0004672
0004702
0005351
0016740
0007186
0006916
0006915
0005975
0006006
0005978
0008286
0048009
0006809
0006468
0006445
0009408
0007165
0006810
0005737
0005634
0016301
0005515
0004674
0004713
0042640
0008637
0007281
0005977
0006954
0043066
0030163
0016567
0006417
0045884
0030027
0005819
0030307
0006412
Swiss-Prot Accession P31749
Q6ZMW5
Q9BV07
P31750
P47196
Unigene ID Hs.525622
Mm.6645
Rn.11422