Protein : ATF4
Owner Public
URN urn:agi-llid:468
Hugo ID 786
Connectivity 251
Name ATF4
Description activating transcription factor 4
Notes binds GABA(B) receptors; may play a role in regulation of activity dependent gene expression [RGD]
RGD ID 621863
MGI ID 88096
Cell Localization Nucleus
Pathway MAPK-ERK in Growth and Differentiation
Inhibition of Apoptosis
MAPK signaling
Group Transcription factors
gluconeogenesis
amino acid metabolism
transcription
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-dependent
response to stress
cytoplasm
nucleus
transcription factor complex
protein binding
DNA binding
sequence-specific DNA binding
transcription factor activity
protein C-terminus binding
protein dimerization activity
GABA receptor binding
transcriptional activator activity
specific RNA polymerase II transcription factor activity
GenBank ID NC_000022
NM_001675
NP_001666
NM_182810
NP_877962
NT_011520
NW_927628
AC_000065
AL022312
CAB45284
AK057751
BC008090
AAH08090
BC011994
AAH11994
BC016855
AAH16855
BC022088
AAH22088
BC024775
AAH24775
BC044895
AAH44895
BC073754
AAH73754
BC073990
AAH73990
CR450353
CAG29349
CR456384
CAG30270
CR590198
CR591677
CR592048
CR595416
CR596727
CR599519
CR601074
CR602573
CR603180
CR604584
CR604900
CR605268
CR605724
CR605899
CR605980
CR606384
CR606595
CR606709
CR607769
CR610045
CR610254
CR610256
CR611425
CR614389
CR614692
CR616253
CR617911
CR619870
CR621381
CR623334
CR625158
CR625892
D90209
BAA14234
M86842
AAA52071
P18848
Q6ICP0
Q96AQ3
NC_000081
NM_009716
NP_033846
NT_039621
NW_000106
NW_001030577
AC_000037
AC140267
AB012277
BAA25314
AK003001
BAC25014
AK138657
BAE23736
AK144777
BAE26060
AK146193
BAE26967
AK150231
AK155254
BAE33149
AK156298
BAE33662
AK157839
BAE34220
AK195416
BC031542
BC085169
AAH85169
BG073595
BG086322
L13791
AAA40476
M94087
AAA53043
X61507
CAA43723
Q06507
Q5U4B2
Q61328
Q8CF69
NC_005106
NM_024403
NP_077379
NW_001088859
NW_047780
AF252627
AAG31732
BC061546
AAH61546
Source Curated
LocusLink ID 468
11911
79255
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 604064
Alias CREB2
TXREB
CREB-2
TAXREB67
activating transcription factor 4
cAMP response element-binding protein 2
Atf-4
C/ATF
MGC96460
activating transcription factor ATF-4
GO ID 0046983
0043565
0003704
0003700
0016563
0006520
0006094
0045944
0006355
0006950
0006350
0005737
0005634
0003677
0005515
0005667
0050811
0008022
Swiss-Prot Accession P18848
Q6ICP0
Q96AQ3
Q06507
Q5U4B2
Q61328
Q8CF69
Unigene ID Hs.496487
Mm.641
Rn.2423