Regulation :

Effect unknown
Mechanism unknown
Owner Public
URN urn:agi-Regulation:inout-urn:agi-llid:7132:out-urn:agi-llid:843::unknown:unknown
Entities TNFRSF1A ---> CASP10
References 1
Connectivity 2

MedLine Reference 9228018:1133
Sentence Binding of FLAME-1, its FDH regions, or the viral proteins to the caspases Mch4 or Mch5 or the adaptor molecule FADD blocks Fas/TNFR1-induced apoptosis possibly by interfering with the assembly of a functional death receptor signaling complex.
Source Curated