Binding :


Connectivity	2
Owner	Public
URN	urn:agi-Binding:inout-urn:agi-go:0004718:inout-urn:agi-complex:3000112:
Entities	JAK ---- Phosphatidylinositol 3-kinase
References	2


MedLine Reference	10438468:1234
Sentence	The mechanism of IL-6-induced activation of PI 3-kinase remains unclear, although JAK can bind PI 3-kinase upon activation of gp130 ( 51 ).
Organ	heart
CellType	myocyte
Journal	J. Biol. Chem
Journal Reference	v274 i33 p23013 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/33/23013
Source	Curated


MedLine Reference	10681570:1223
Sentence	In addition, recent reports have shown the interaction of PI3K with mitogen-activated protein kinase ( 48 ) or Janus kinase/signal transducers and activators of transcription ( 49 ) when cells were stimulated by GM-CSF .
CellType	macrophage
Journal	J. Biol. Chem
Journal Reference	v275 i8 p5810 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/8/5810
Organism	mouse
Source	Curated