Expression :

Owner Public
URN urn:agi-Expression:inout-urn:agi-llid:2308:out-urn:agi-llid:356::positive
Entities FOXO1A --+> TNFSF6
References 7
Connectivity 2
Effect positive
MedLine Reference 12482965:10257
Sentence Activated androgen receptor suppresses FKHR-induced Fas ligand expression.
Journal Mol. Cell. Biol
Journal Reference v23 i1 p104
Journal Link http://mcb.asm.org/cgi/content/full/23/1/104
MedLine Reference 15194686:10243
Sentence The Foxo1 is a target of Akt action, and can mediate the negative regulatory effects of insulin on the IGFBP-1 and the Fas ligand gene promoters ( 37 , 38 ).
Journal J. Biol. Chem
Journal Reference v279 i35 p36650
Journal Link http://www.jbc.org/cgi/content/full/279/35/36650
Organism Rattus norvegicus
MedLine Reference 11524433:10035
Sentence Phosphorylation of Forkhead 1 by Akt prevents it from inducing expression of the cytotoxic factor FasL whose synthesis after growth factor withdrawal plays a role in causing neuronal apoptosis by initiating a caspase cascade ( Brunet et al., 1999 ; Le-Niculescu et al., 1999 ; Raoul et al., 1999 ).
Journal J. Cell Biol
Journal Reference v154 i5 p995
Journal Link http://www.jcb.org/cgi/content/full/154/5/995
Organism Rattus norvegicus
MedLine Reference 131103894:11145
MedLine Reference 106100567:11176
Journal EMBO
Journal Reference v24 i5 p7600570
Journal Link http://www.nature.com/emboj/journal/v24/n5/full/7600570a.html
MedLine Reference 12482965:1258
Sentence Activated androgen receptor suppresses FKHR-induced Fas ligand expression.
Journal Mol. Cell. Biol
Journal Reference v23 i1 p104 (2003)
Journal Link http://mcb.asm.org/cgi/content/full/23/1/104
CellLineName DU 145
Source Curated
MedLine Reference 11524433:1035
Sentence Phosphorylation of Forkhead 1 by Akt prevents it from inducing expression of the cytotoxic factor FasL whose synthesis after growth factor withdrawal plays a role in causing neuronal apoptosis by initiating a caspase cascade ( Brunet et al., 1999 ; Le-Niculescu et al., 1999 ; Raoul et al., 1999 ).
CellType neural
Journal J. Cell Biol
Journal Reference v154 i5 p995 (2001)
Journal Link http://www.jcb.org/cgi/content/full/154/5/995
Organism mouse
Source Curated