Regulation :

Effect negative
Owner Public
URN urn:agi-Regulation:inout-urn:agi-go:0008189:out-urn:agi-llid:836::negative
Entities apoptosis inhibitor ---| CASP3
References 6
Connectivity 2
MedLine Reference 11818445:1
Sentence Inhibitors of apoptosis proteins (IAP) bind to and inhibit caspases 3, 7, and 9 activity and the induction of apoptosis.
MedLine Reference 15662549:8
Sentence On evaluating inhibitors of apoptosis, we found up-regulation of caspase-3 and -7-inhibiting X-linked inhibitors of apoptosis in diabetic rats.
Organism Rattus norvegicus
MedLine Reference 10803595:10190
Sentence The activation of caspase-3 can be inhibited by inhibitors of apoptosis proteins such as Xiap (X-chromosome-linked inhibitor of apoptosis protein) ( 23 , 24 ).
Journal Endocrinology
Journal Reference v141 i5 p1846
Journal Link http://endo.endojournals.org/cgi/content/full/141/5/1846
Organism Rattus norvegicus
MedLine Reference 15014070:10031
Journal J. Biol. Chem
Journal Reference v279 i21 p22020
Journal Link http://www.jbc.org/cgi/content/full/279/21/22020
Organism Mus musculus
MedLine Reference 15728125:10053
Journal Blood
Journal Reference v105 i11 p4247
Journal Link http://www.bloodjournal.org/cgi/content/full/105/11/4247
Organism Mus musculus
MedLine Reference 10803595:1191
Sentence The activation of caspase-3 can be inhibited by inhibitors of apoptosis proteins such as Xiap (X-chromosome-linked inhibitor of apoptosis protein) ( 23 , 24 ).
Journal Endocrinology
Journal Reference v141 i5 p1846 (2000)
Journal Link http://endo.endojournals.org/cgi/content/full/141/5/1846
Organism rat
Source Curated