Protein : CEBPB


Owner	Public
URN	urn:agi-llid:1051
Hugo ID	1834
Connectivity	753
Name	CEBPB
Description	CCAAT/enhancer binding protein (C/EBP), beta
Notes	transcription factor that binds to CCAATT motif on DNA and may facilitate IL-6 induced transcriptional activation [RGD]


RGD ID	2327


MGI ID	88373


Cell Localization	Nucleus


Pathway	Jak-Stat Pathway from IL6 Receptor
	IL-6 signaling
	IL-1 and IL-6 signaling
	VIPR1 -> CEBPB signaling pathway
	IL6R -> CEBPB signaling pathway
	ITGAM/ITGB2 -> CEBPB signaling pathway
	NGFR -> CEBPB signaling pathway


Group	Transcription factors
	neuron differentiation
	fat cell differentiation
	anti-apoptosis
	induction of apoptosis
	regulation of interleukin-6 biosynthesis
	transcription
	positive regulation of transcription
	regulation of transcription, DNA-dependent
	transcription from RNA polymerase II promoter
	embryonic placenta development
	inflammatory response
	acute-phase response
	cytoplasm
	nucleus
	protein binding
	DNA binding
	sequence-specific DNA binding
	transcription factor activity
	protein dimerization activity
	protein homodimerization activity
	protein heterodimerization activity
	transcriptional activator activity


Source	Curated


OMIM ID	189965


Alias	LAP
	CRP2
	TCF5
	IL6DBP
	NF-IL6
	MGC32080
	C/EBP-beta
	CCAAT/enhancer binding protein beta
	transcription factor 5
	nuclear factor of interleukin 6
	interleukin 6-dependent DNA-binding protein
	liver-enriched transcriptional activator protein
	NF-M
	Nfil6
	IL-6DBP
	C/EBP BETA
	nuclear protein Il6
	nuclear factor-IL6
	liver activating protein (LAP)
	Liver activating protein (LAP also NF-IL6 nuclear factor-IL6 previously designated TCF5)
	Liver activating protein (LAP, also NF-IL6, nuclear factor-IL6, previously designated TCF5)