Protein : IL6ST


Owner	Public
URN	urn:agi-llid:3572
Hugo ID	6021
Connectivity	492
Name	IL6ST
Description	interleukin 6 signal transducer
Notes	IL-6 signal transducing molecule [RGD]


RGD ID	2903


MGI ID	96560


Cell Localization	Plasma membrane


Pathway	Jak-Stat Pathway from IL6 Receptor
	LIF
	Cardiotrophin-1 like
	CNTF
	Cardiotrophin-1
	IL11
	IL-6 signaling
	IL6
	oncostatin M
	IL-1 and IL-6 signaling
	G-CSF
	OSMR -> STAT3 signaling pathway
	IL11R -> STAT3 signalling pathway
	IL6R -> CEBPB signaling pathway
	IL6R -> ELK1-SRF signaling pathway
	IL6R -> ELK4-SRF signaling pathway
	IL6R -> STAT1 signaling pathway
	IL6R -> STAT3 signaling pathway
	IL6ST -> STAT5B signaling pathway
	LIFR -> STAT5A signaling pathway
	LIFR/CNTFR -> STAT3 signaling pathway


Group	Receptors
	signal transduction
	regulation of hormone secretion
	cell surface receptor linked signal transduction
	regulation of Notch signaling pathway
	positive regulation of cell growth
	positive regulation of cell proliferation
	immune response
	membrane
	plasma membrane
	integral to membrane
	integral to plasma membrane
	extracellular space
	protein binding
	interleukin-6 receptor activity
	cytokine activity
	receptor activity
	hematopoietin-interferon-class (D200-domain) cytokine receptor activity
	oncostatin-M receptor activity


Source	Curated


OMIM ID	600694


Alias	CD130
	GP130
	CDw130
	IL6R-beta
	GP130-RAPS
	interleukin 6 signal transducer
	CD130 antigen
	IL6ST nirs variant 3
	oncostatin M receptor
	gp130 transducer chain
	membrane glycoprotein gp130
	interleukin receptor beta chain
	gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form
	AA389424
	BB405851
	D13Ertd699e
	5133400A03Rik
	Ac1055