Protein : PFN1
Owner Public
URN urn:agi-llid:5216
Hugo ID 8881
Connectivity 95
Name PFN1
Description profilin 1
Notes regulates actin polymerization; may reorganize the actin cytoskeleton; may be involved in the pathogenesis of glomerulonephritis [RGD]
RGD ID 621825
MGI ID 97549
Pathway Erk-PI3K in Collagen Binding
Group cytoskeleton organization and biogenesis
actin cytoskeleton organization and biogenesis
actin polymerization and-or depolymerization
regulation of actin polymerization and-or depolymerization
sequestering of actin monomers
regulation of transcription from RNA polymerase II promoter
neural tube closure
cytoplasm
nucleus
cytoskeleton
actin cytoskeleton
protein binding
actin binding
actin monomer binding
GenBank ID NC_000017
NM_005022
NP_005013
NT_010718
NW_926584
AC_000060
AC109333
BC002475
AAH02475
BC006768
AAH06768
BC013439
AAH13439
BC015164
AAH15164
BC057828
AAH57828
BT007001
AAP35647
CR407670
CAG28598
CR612678
D28377
BAA05743
J03191
AAA36486
P07737
Q53Y44
NC_000077
NM_011072
NP_035202
NT_096135
NT_114258
NW_000039
NW_001030480
AC_000033
AL596117
CAI25168
CAI25169
CR933736
AJ279848
AK011066
BAB27373
AK028117
BAC25757
AK131636
AK150780
BAE29845
AK152491
BAE31262
AK160191
BAE35684
BC002080
AAH02080
X14425
CAA32586
P62962
Q5SX49
Q5SX50
NC_005109
NM_022511
NP_071956
NW_001084656
NW_047334
AC_000078
BC062405
AAH62405
X96967
CAA65655
P62963
Source Curated
LocusLink ID 5216
18643
64303
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 176610
Alias profilin 1
profilin-1
Pfn
RP23-326P7.1
actin binding protein
GO ID 0003785
0030036
0007010
0015629
0003779
0005515
0001843
0008064
0006357
0042989
0005737
0005856
0005634
0008154
Swiss-Prot Accession P07737
Q53Y44
P62962
Q5SX49
Q5SX50
P62963
Unigene ID Hs.494691
Mm.2647
Rn.1152