Protein : GSN


Owner	Public
URN	urn:agi-llid:2934
Hugo ID	4620
Connectivity	368
Name	GSN
Description	gelsolin
Notes	plays a role in phosphoinositide mediated disassembly of actin filaments in Sertoli cell adhesion complexes; may regulate sperm release and turnover of the blood-testis barrier [RGD]


RGD ID	1303089


MGI ID	95851


Cell Localization	Nucleus


Pathway	Erk-PI3K in Collagen Binding


Group	Cytoskeleton
	regulation of cell adhesion
	phosphoinositide-mediated signaling
	actin filament severing
	actin filament polymerization
	barbed-end actin filament capping
	vesicle-mediated transport
	extracellular region
	lamellipodium
	cytoplasm
	cytosol
	cytoskeleton
	actin cytoskeleton
	extracellular space
	structural molecule activity
	protein binding
	calcium ion binding
	actin binding


GenBank ID	NC_000009
	NM_198252
	NP_937895
	NM_000177
	NP_000168
	NT_008470
	NW_924573
	AC_000052
	AL049930
	AL513122
	CAI14413
	CAI14414
	CAI14415
	CAI14417
	CAI14418
	AI742454
	AK092797
	AK096280
	AK125819
	AL832070
	CAH10407
	BC017491
	AAH17491
	BC026033
	AAH26033
	BX647999
	CR596569
	CR618098
	DA294394
	DB250757
	X04412
	CAA28000
	P06396
	Q5T0H7
	Q5T0H8
	Q5T0I0
	Q5T0I1
	Q5T0I2
	Q69YR8
	NC_000068
	NM_146120
	NP_666232
	NT_039206
	NW_000175
	NW_001030686
	AC_000024
	AL773523
	AK076156
	BAC36223
	AK089934
	BAC41004
	AK135632
	AK143664
	BAE25485
	AK146969
	BAE27574
	AK148957
	BAE28702
	AK150359
	BAE29494
	AK151684
	BAE30608
	AK153029
	BAE31661
	AK166831
	BAE39054
	AK166932
	BAE39126
	AK167918
	BAE39925
	AK168461
	BAE40358
	AK168532
	BAE40410
	AK168707
	BAE40549
	AK168725
	BAE40566
	AK168829
	AK169041
	BAE40830
	AK169670
	BAE41291
	AK178123
	AK181095
	AK188287
	AK188608
	AK192738
	AK196436
	AK197869
	AK203676
	AK205294
	AK206117
	AK212201
	AK213866
	AK217606
	AK218612
	AK219663
	AK219732
	BC023143
	AAH23143
	BC060377
	AAH60377
	BG085962
	J04953
	AAA37677
	P13020
	NC_005102
	NM_001004080
	NP_001004080
	NW_001084810
	NW_047653
	AC_000071
	BC079472
	AAH79472


Source	Curated


LocusLink ID	2934
	227753
	296654


Organism	Homo sapiens
	Mus musculus
	Rattus norvegicus


OMIM ID	137350
	105120


Alias	DKFZp313L0718
	gelsolin
	MGC28083
	MGC95032


GO ID	0003779
	0005509
	0005515
	0030041
	0051014
	0051016
	0015629
	0005829
	0005576
	0005198
	0016192
	0005737
	0005856
	0005615
	0030027
	0048015
	0030155


Swiss-Prot Accession	P06396
	Q5T0H7
	Q5T0H8
	Q5T0I0
	Q5T0I1
	Q5T0I2
	Q69YR8
	P13020


Unigene ID	Hs.522373
	Mm.21109
	Rn.103770