Protein : JUN


Owner	Public
URN	urn:agi-llid:3725
Hugo ID	6204
Connectivity	2509
Name	JUN
Description	Jun oncogene
Notes	transcription factor; acts as a protooncogene [RGD]


RGD ID	2943


MGI ID	96646


Cell Localization	Nucleus


Pathway	Jnk-mapk
	FAS signaling
	Jak-Stat Pathway from IL6 Receptor
	Insulin pathway
	EGF signaling
	PDGF signaling
	TNFR1 signaling
	Erythropoietin signaling
	IL-6 signaling
	SAPK-JNK Signaling
	ATM signaling
	Toll-Like Receptor pathway
	IL-2 signaling
	NGF signaling
	IL1
	Integrin Signaling
	EDG3/5 -> AP-1 signaling pathway
	EGFR -> AP-1 signaling pathway
	NTRKs -> AP-1 signaling pathway
	B-cell receptor -> AP-1 signaling pathway
	F2R -> AP-1 signaling pathway
	ENDRA -> AP-1 signaling pathway
	ENDRB -> AP-1 signaling pathway
	PTAFR -> AP-1 signaling pathway
	T-cell receptor -> AP-1 signaling pathway
	CD19 -> AP-1 signaling pathway
	CD22/72 -> AP-1 signaling pathway
	ADORA1 -> AP-1 signaling pathway
	TGFBR -> AP-1 signaling pathway
	Frizzled -> JUN signaling pathway
	ITGB1 -> AP-1 signaling pathway
	CD38 -> AP-1 signaling pathway
	TLR2/4/5/7/9 -> AP-1 signaling pathway
	GFRs -> AP-1 signaling pathway
	TLR2/6 -> AP-1 signaling pathway
	TNFRs -> AP-1 signaling pathway
	NGFR -> AP-1 signaling pathway
	ICAM1 -> AP-1 signaling pathway
	TNFRSF1A -> AP-1 signaling pathway
	DRD2 -> AP-1 signaling pathway
	EDARs -> AP-1 signaling pathway


Group	Transcription factors
	cellular physiological process
	leading edge cell differentiation
	regulation of progression through cell cycle
	transcription
	positive regulation of transcription from RNA polymerase II promoter
	regulation of transcription, DNA-dependent
	transcription from RNA polymerase II promoter
	intracellular
	nucleus
	nuclear chromosome
	transcription factor complex
	protein binding
	DNA binding
	sequence-specific DNA binding
	transcription factor activity
	double-stranded DNA binding
	protein dimerization activity
	protein homodimerization activity
	protein heterodimerization activity
	RNA polymerase II transcription factor activity
	transcriptional activator activity


Source	Curated


OMIM ID	165160


Alias	AP1
	v-jun avian sarcoma virus 17 oncogene homolog
	activator protein 1
	enhancer-binding protein AP1
	Jun activation domain binding protein
	AP-1
	Junc
	c-jun
	Jun oncogene
	immediate early gene
	v-jun sarcoma virus 17 oncogene homolog
	Avian sarcoma virus 17 (v-jun) oncogene homolog
	v-jun sarcoma virus 17 oncogene homolog (avian)